Prevalence of respiratory syncytial virus infection among Philippino children with bronchiolitis
L. U. Grino, A. R. Mendoza, M. C. G. Fung, M. T. Valencia, M. I. M. Atienza, J. C. Bernardo, Z. C. Miranda, C. C. Cala (Quezon City, The Philippines)
Source: Annual Congress 2002 - Bronchiolitis
Session: Bronchiolitis
Session type: Oral Presentation
Number: 238
Disease area: Paediatric lung diseases, Respiratory infections
Abstract Purpose: The purpose of this study is to determine the prevalence of Respiratory Syncytial Virus (RSV) infection among Filipino pediatric patients with acute bronchiolitis using an immunoflourescent (IF) technique. Methods: Children 2 months to 36 months with a diagnosis of acute bronchiolitis seen at St. Luke's Medical Center and National Children's Hospital from July 2001 to October 2001 were included in the study. Clinical condition was evaluated using a modified Respiratory Distress Assessment Instrument (RDAI) score. Age, sex and the degree of respiratory distress were obtained. Specimen was collected from the nasopharynx for IF testing and analyzed. Data analysis was done using SPSSW. Result: 116 patients with acute bronchiolitis were analyzed for RSV. The mean age of the sample population is 7.41 ±] 5.51 (range 2-36 months). IF test that yielded positive for RSV was 39.7%, majority belonged to the 7-12 months age group which accounted to 43.5%. The mean age of subjects who were tested positive was 8.74 ±] 5.65 months with more males tested positive than females (60.9% vs 39.1%). Sixty one percent of RSV positive had moderate respiratory distress. Conclusion: RSV is an important agent causing acute bronchiolitis among Filipino children with a prevalence of 39.7%. Clinical Implication: Identification of the viral etiologic cause of acute bronchiolitis or any lower respiratory tract infection is cost-effective and the indescriminate use of antibiotics in infants and children could be prevented.
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L. U. Grino, A. R. Mendoza, M. C. G. Fung, M. T. Valencia, M. I. M. Atienza, J. C. Bernardo, Z. C. Miranda, C. C. Cala (Quezon City, The Philippines). Prevalence of respiratory syncytial virus infection among Philippino children with bronchiolitis. Eur Respir J 2002; 20: Suppl. 38, 238
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