Home assessment of respiratory resistance by forced oscillation in asthmatic patients. Feasibility and reproducibility of unsupervised patient self-testing

D. Navajas, J. Rigau, L. Buscemi, F. Burgos, J. Roca, R. Farré (Barcelona, Spain)

Source: Annual Congress 2002 - Lung mechanics: from laboratory to bedside
Session: Lung mechanics: from laboratory to bedside
Session type: Oral Presentation
Number: 188
Disease area: Airway diseases, Paediatric lung diseases

Congress or journal article abstract

Abstract

The forced oscillation technique (FOT) requires minimal patient cooperation to measure respiratory resistance (Rrs). Therefore, FOT could be suitable for the routine home monitoring of airway obstruction in patients with asthma. Nevertheless, as FOT measurements have been usually carried out by technicians in the lung function lab, there are currently no data on the applicability of unsupervised patient self-testing. Aim: To assess the feasibility of FOT and the reproducibility of Rrs data in routine home self-testing in asthmatic patients. Methods: The study was carried out in 6 patients with well characterised asthma. Patients at home were trained on FOT for 15 min and were provided with a recently developed portable FOT device (Rigau, J. et al Eur Respir J 2002; 19:146-150 ) for a period of at least 10 days. Each morning the patient measured his/her Rrs by consecutively performing 4 FOT measurements (5 Hz, 16 s each). Results: All the patients were able to carry out reproducible Rrs measurements. The coefficient of variation (CV; mean±]SD) on the first day was CV(Rrs)=9.7±]7.3% (range: 2.7% - 23.0%). CV(Rrs) did not vary significantly (paired t-tests; p>0.05) with time: on day 5, CV(Rrs)=8.7±]6.4% (range: 4.2% - 21.1%); and on day 10, CV(Rrs)=10.7±]5.6% (range: 6.0% - 19.9%). These CV(Rrs) values were similar to the ones reported in FOT measurements carried out by technicians in the lung function lab. Conclusion: As unsupervised patient self-testing at home is feasible and reproducible, FOT could be a useful tool for the routine monitoring of airway obstruction in asthma.
Supported in part by CICYT (SAF99-0001) and European Comission (CHRONIC; IST_DGXIII,1999-12158)


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D. Navajas, J. Rigau, L. Buscemi, F. Burgos, J. Roca, R. Farré (Barcelona, Spain). Home assessment of respiratory resistance by forced oscillation in asthmatic patients. Feasibility and reproducibility of unsupervised patient self-testing. Eur Respir J 2002; 20: Suppl. 38, 188

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