Thrombin activates mitogen activated protein (MAP) kinase and activated protein-1 (AP-1) to induce interleukin-8 (IL-8) release from airway epithelial cells Source: Annual Congress 2003 - Mechanisms of lung injury: from bench to bedside Year: 2003
Transforming growth factor-α (TGF-α)-induced interleukin-8 (IL-8) release in human bronchial epithelial cells in vitro: role of mitogen-activated protein kinases (MAPK) Source: Eur Respir J 2002; 20: Suppl. 38, 573s Year: 2002
Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure Source: Eur Respir J 2005; 25: 797-803 Year: 2005
Transforming growth factor-β inhibition of lung fibroblast proliferation is mediated through prostaglandin E2 , via activation of p38 mitogen-activated protein kinase Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005
Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008
Eosinophil adhesion to cholinergic nerve cells induces NFκB activation via the interleukin-1 receptor associated kinase (IRAK) pathway and upregulates ICAM-1 expression Source: Eur Respir J 2003; 22: Suppl. 45, 10s Year: 2003
Mitogen-activated protein-kinase modulation of NF-kappaB-induced GM-CSF release from human alveolar macrophages Source: Eur Respir J 2003; 22: Suppl. 45, 392s Year: 2003
Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages Source: Eur Respir J 2004; 23: 805-812 Year: 2004
Regulation of cytokine- and phorbol ester-mediated interleukin (IL)-8 expression in the absence or presence of pyocyanin in human bronchial epithelial cell line: roles of protein kinase C and mitogen-activated protein kinases Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
Group V phospholipase A2 (gVPLA2 ) -induced eosinophil synthesis of LTC4 is independent of mitogen-activated protein kinases (MAPK) activation Source: Eur Respir J 2001; 18: Suppl. 33, 408s Year: 2001
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Inhibition of P38 kinase does not reduce production of TNF-alpha from airway cells in COPD Source: Annual Congress 2007 - Epithelial networks in the airways Year: 2007
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
Activation of second messenger pathways in alveolar macrophages by endotoxin Source: Eur Respir J 2002; 20: 210-222 Year: 2002
Does tumour necrosis factor-alpha (TNF-alpha) induced by lipopolysaccharide have a positive feedback effect on the up-regulation of interleukin-8 (IL-8) messenger RNA by monocytes from COPD patients? Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection Year: 2013
The pan janus kinase (JAK) inhibitor KN-002 suppresses inflammatory mediator release from severe asthma bronchial epithelial cells. Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science Year: 2021
Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
The effects of oral p38 mitogen activated protein kinase (MAPK) inhibitor SB-681323 on blood biomarkers in COPD Source: Annual Congress 2008 - Novel treatments for respiratory disease Year: 2008