Inhibition of fibrinolysis stimulates alveolar wound repair in vitro

C. C. Van Leer, M. Stutz, A. Haeberli, T. K. Geiser (Bern, Switzerland)

Source: Annual Congress 2003 - Induction and modulation of lung cell damage
Session: Induction and modulation of lung cell damage
Session type: Poster Discussion
Number: 3673
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. C. Van Leer, M. Stutz, A. Haeberli, T. K. Geiser (Bern, Switzerland). Inhibition of fibrinolysis stimulates alveolar wound repair in vitro. Eur Respir J 2003; 22: Suppl. 45, 3673

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Role of cigarette smoke-induced cytoxicity in inhibition of epithelial wound repair in vitro
Source: Eur Respir J 2002; 20: Suppl. 38, 96s
Year: 2002

GRX1 enhances wound repair of alveolar epithelial type II cells in vitro
Source: Annual Congress 2009 - Crossing the line: alveolo-capillary barrier control in acute lung injury
Year: 2009

Lipoxin A4 promotes lung epithelial repair whilst inhibiting fibroblast proliferation
Source: ERJ Open Res 2016: 00079-2015
Year: 2016



Prostaglandin-E2 mediated inhibition of TNFα release from human alveolar macrophages
Source: Eur Respir J 2005; 26: Suppl. 49, 223s
Year: 2005

Clara cells directly inhibit alveolar epithelial cell wound repair by inducing apoptosis
Source: Annual Congress 2010 - Novel insights into the pathophysiology of asthma and COPD
Year: 2010


Inhibition of the Arp2/3 complex inhibits lung myofibroblast differentiation in vitro and attenuates bleomycin-induced pulmonary fibrosis in mice
Source: International Congress 2019 – Extracellular matrix formation and remodelling in physiology and disease
Year: 2019

Role of coagulation cascade proteases in lung repair and fibrosis
Source: Eur Respir J 2003; 22: 33S-35S
Year: 2003


Role of coagulation cascade proteases and lung repair and fibrosis
Source: Lung Science Conference 2003 - Inflammation and Respiratory Disease
Year: 2003

PP126 – RANKL contributes to lung tissue repair via promoting type II epithelial cell proliferation
Source: ERS Lung Science Conference 2021
Year: 2021

RANKL contributes to lung tissue repair via promoting type II epithelial cell proliferation
Source: Virtual Congress 2020 – Elucidating the mechanisms underlying lung repair and exploring therapeutic strategies in vitro
Year: 2020




Bronchial epithelial cells synthesise proteins of the extrinsic coagulation cascade to support fibrin formation in response to wounding
Source: Eur Respir J 2005; 26: Suppl. 49, 555s
Year: 2005

Inhibition of bradykinin breakdown by ACE inhibitors reduces mechanical stretch-induced apoptosis of alveolar type II cells
Source: Eur Respir J 2005; 26: Suppl. 49, 345s
Year: 2005

PP205 – Effect of mTOR inhibition in a 3D in vitro model of alveolar epithelium and epithelial regeneration
Source: ERS Lung Science Conference 2021
Year: 2021

COX inhibition enhances remodelling processes in human lung fibroblasts
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Role of thrombin and thrombin receptor in the activation of human bronchial epithelial cells during airway inflammation
Source: Eur Respir J 2007; 30: Suppl. 51, 523s
Year: 2007

A role for PAR-1 in bronchial epithelial repair
Source: Eur Respir J 2005; 26: Suppl. 49, 556s
Year: 2005

Coagulation and fibrinolysis in lung remodelling and repair
Source: Annual Congress 2006 - PG15 - Remodelling and repair in lung disease
Year: 2006

Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair
Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury
Year: 2008


Co-culturing alveolar epithelial with lung micro-vascular endothelial cells attenuates hypoxia-induced alveolar leakage and inhibition of reabsorption
Source: Annual Congress 2009 - Crossing the line: alveolo-capillary barrier control in acute lung injury
Year: 2009