Source: Annual Congress 2003 - Assessing airway function: practicalities and clinical applications
Disease area: Airway diseases

Abstract

It is known that there is some relation between airways obstruction and the gastro-oesophageal reflux (GER) disease. Some authors found an increased prevalence of GER symptoms in patients with COPD.
We have examined 58 patients with COPD divided in groups: 1)gr: 20 subjects with mild obstruction with FEV1>65%;and 2)gr: 18 subjects with moderate obstruction with FEV1 between 65% and 45%; and 20 subjects with severe obstruction with FEV1<45%. We have also a control group of 12 healthy subjects. The groups completed their self-reported questionnaire about symptoms like: heartburn, acid-regurgitation, dysphagia, chronic cough, dyspnoea.
Patients with COPD and significant GER symptoms had respiratory symptoms associated with reflux events. Greater proportion of COPD patients had significant GER symptoms defined as regurgitation and dysphagia once or more per week. COPD patients with forced expiratory volume in one second (FEV1)<45% showed more prevalent GER symptoms compared to those with values of FEV1>45%.
We concluded that the prevalence of gastro-oesophageal reflux symptoms is high in patients with COPD. GER symptoms are more prevalent in patients with COPD with severe airways obstruction when compared to less airways obstructed group and controls. We suggest an association between the degree of airways obstruction in COPD patients and the increased rate of GER symptoms.

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Z. M. Goseva, D. V. Dokic, M. I. Boskovska, K. Busljetic, Z. S. Arsovski (Skopje, Macedonia). Measurments of forced expiratory volume in one second (FEV1) and gastro-oesophageal reflux (GER) symptoms in COPD. Eur Respir J 2003; 22: Suppl. 45, 3620

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