Source: Annual Congress 2003 - Pulmonary hypertension
Disease area: Pulmonary vascular diseases

Abstract

Introduction: The vascular disorders presented in patients with chronic liver disease are variable, like hepatopulmonary syndrome with the predominance of intrapulmonary vascular dilatations and portopulmonary hypertension with elevated pressure in pulmonary arterial system. This two disorders can be presented in a same patient, but there are so few cases related.
Aim: to determine the prevalence of these two disorders in a same patient, in a group of cirrhotic patients who will be submitted to hepatic transplantation.
Methods: In a group of 112 patients with the diagnosis of chronic liver disease who will be submitted to hepatic transplantation. From this group all patients were submitted to Chest X-Ray, arterial blood gases analysis, Alveolar-arterial gradient(AAG) calculated, Doppler echorcardiography with mensuration of tricuspid regurgitation jet and systolic pulmonary blood pressure determination and intrapulmonary shunt determination by the infusion of saline solution in a brachial vein. We consider pulmonary hypertension in that cases that the tricuspideal regurgitation was superior to 40 mmHg, and hepatopulmonary syndrome in the cases that the AAG was superior to 15mmHg with positive pulmonary shunt confirmed by the Doppler echocardiography.
Results: We found the two disorders presented in same patients in 13 cases (11,6%) of this studied group.
Conclusion: The association between the two disorders in this group has an elevated frequency. Their coexistences need to be more evaluated in cirrhotic patients.

Rating:

Share or cite this content

Citations should be made in the following way:
E. Garcia, A. I. Zille, J. S. Moreira, A. B. Brandao (Porto Alegre, Brazil). Association between portopulmonary hypertension and hepatopulmonary syndrome in cirrhotics, candidates to hepatic transplantation. Eur Respir J 2003; 22: Suppl. 45, 3534

Member's Comments

No comment yet.

Related content which might interest you: Liver transplantation in hepatopulmonary syndrome and portopulmonary hypertension Source: Annual Congress 2003 - Pulmonary-hepatic disorders (PHD) - recommendations of the PHD ERS Task Force for management of hepatopulmonary syndrome and portopulmonary hypertension Year: 2003 Portopulmonary hypertension and hepatopulmonary syndrome: a clinician-oriented overview Source: Eur Respir Rev 2012 21:223-233 Year: 2012 The lung in liver disease: hepatopulmonary syndrome and portopulmonary hypertension Source: Eur Respir Monogr 2019; 86: 262-277 Year: 2019 Hepatopulmonary syndrome among patients of cirrhosis of liver and portal hypertension Source: Annual Congress 2007 - Pulmonary circulation Year: 2007 Development of hepatopulmonary syndrome during combination therapy for portopulmonary hypertension Source: Eur Respir J, 53 (1) 1801880; 10.1183/13993003.01880-2018 Year: 2019 The hepatopulmonary syndrome Source: ISSN=ISSN 1025-448x, ISBN=ISBN 1-904097-39-1, page=112 Year: 2005 Sildenafil for patients with portopulmonary hypertension, candidates to hepatic transplant Source: Eur Respir J 2004; 24: Suppl. 48, 109s Year: 2004 Resolution of portopulmonary hypertension (POPH) following liver transplantation Source: Annual Congress 2012 - Pulmonary circulation: clinical aspects of PAH and associated PH Year: 2012 Intravenous iloprost bridging to orthotopic liver transplantation in portopulmonary hypertension Source: Eur Respir J 2004; 24 : 703-707 Year: 2004 The prevalence of hepatopulmonary syndrome in 445 patients, candidates to hepatic transplant Source: Eur Respir J 2004; 24: Suppl. 48, 562s Year: 2004 Outcome of candidates for liver transplantation suffering from portopulmonary hypertension Source: Annual Congress 2013 –Pulmonary circulation: clinical pulmonary hypertension I Year: 2013 Hepatopulmonary syndrome following portopulmonary hypertension Source: Eur Respir J 2007; 29: 1277-1280 Year: 2007 An autopsy case of portopulmonary hypertension associated with idiopathic portal hypertension Source: Annual Congress 2013 –Pulmonary circulation: clinical pulmonary hypertension II Year: 2013 The prevalence of pulmonary hypertension in cirrhotic patients submitted to hepatic transplantation Source: Eur Respir J 2003; 22: Suppl. 45, 465s Year: 2003 Characteristics of the hepatopulmonary syndrome in cirrhotic patients, pre and postransplantation Source: Eur Respir J 2006; 28: Suppl. 50, 546s Year: 2006 Portopulmonary hypertension Source: ISSN=ISSN 1025-448x, ISBN=ISBN 1-904097-39-1, page=129 Year: 2005 Liver transplantation for hepatopulmonary syndrome : a ten-year experience in Paris, France. Liver transplantation for hepatopulmonary syndrome Source: Eur Respir J 2002; 20: Suppl. 38, 348s Year: 2002 Prognostic significance of the hepatopulmonary syndrome in liver cirrhosis Source: Eur Respir J 2002; 20: Suppl. 38, 447s Year: 2002