Source: Annual Congress 2003 - COPD: a multicomponent disease
Disease area: Airway diseases

Abstract

Accounting the combination of pathology among the patients up-wards 50 years, the study of interference of different illnesses is very actual. The aim of investigation was to make a comparative analysis of lung function in patients with COPD and in patients with combination COPD and diabetes with body mass index more than 30. Magnitudes of lung function: FVC, FEV₁, FEV₁/ FVC (% pred) were analyzed during exacerbation and remission. In the 1 group patients with COPD (n=60), middle age 54,6±1,03 were included. The 2 group consisted of patients with combination COPD and diabetes with body mass index more than 30 (n=60), middle age 53,1±0,94. In 1 group magnitudes of lung function were: in acute period FVC64,81±1,11, in remission 69,88±1,31 (p<0,002); FEV₁ 35,60±0,96 and 41,32±1,44 (p<0,002); FEV₁ /FVC 54,93±1,17 and 59,12±0,98 (p<0,005). In the 2 group accordingly: FVC 60,48±0,76 and 62,35±0,92 (p>0,05); FEV₁ 31,29±1,14 and 34,89 ±0,99 (p>0,05); FEV₁ /FVC 51,73±1,25 and 55,96±1,14 (p>0,05). Initially, magnitudes of lung function in the 1 group were statistically better in comparison with the same magnitudes in the 2 group. Dynamic of lung function was practically absent in the 2 group after treatment. Thus, combination COPD and diabetes with body mass index more than 30 affects adversely to the lung function and treatment outcomes, this charges the clinical presentations of COPD.

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Citations should be made in the following way:
I. V. Grebneva, G. L. Ignatova, L. A. Stepanisheva (Chelyabinsk, Russia). Lung function in the patients with COPD and with the combination COPD and grownup's diabetes. Eur Respir J 2003; 22: Suppl. 45, 3367

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