Echocardiographic abnormalities in patients with COPD entering pulmonary rehabilitation

S. Wilke, M. Spruit, M. Otkinska, N. Lencer, L. Vanfleteren, E. Wouters, F. Franssen (Horn, Maastricht, Netherlands)

Source: Annual Congress 2013 –The best abstracts in pulmonary rehabilitation and chronic care (sponsored by MOTEK Medical)
Disease area: Airway diseases, Pulmonary vascular diseases

Congress or journal article abstractE-poster

Abstract

Purpose: We aimed to study echocardiographic abnormalities in patients with COPD entering pulmonary rehabilitation (PR).
Methods: Demographic and clinical characteristics were assessed in 160 stable patients with mild to very severe COPD during a pre-rehabilitation assessment. In addition, all patients underwent echocardiographic evaluation. The relationship between lung function and left ventricular ejection fraction (LVEF) was assessed.
Results: Cardiovascular abnormalities were detected in 69 of the 160 (43.8%) patients with COPD (41.3% female, mean (SD) age 63.3 (9.3) years, FEV1 46.49 (19.2)% predicted). Decreased LVEF (46.4%), left ventricular hypertrophy (27.5%), elevated right ventricular systolic pressure and valvular dysfunction (both 10.1%) were most prevalent. Forty-two of the 69 patients did not have echocardiographic abnormalities in their medical history. There was no relationship between FEV1 and LVEF.Conclusions: Almost half of the patients with mild to very severe COPD entering PR had echocardiographic abnormalities. Indeed, in 61% of these cases, the abnormalities were previously undetected. These findings underline the complexity of patients with COPD entering PR and the importance of echocardiography as an assessment tool for patients with COPD.
This study was financially supported by Lung Foundation Netherlands (3.4.10.015) and GlaxoSmithKline (SCO115406).


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S. Wilke, M. Spruit, M. Otkinska, N. Lencer, L. Vanfleteren, E. Wouters, F. Franssen (Horn, Maastricht, Netherlands). Echocardiographic abnormalities in patients with COPD entering pulmonary rehabilitation. Eur Respir J 2013; 42: Suppl. 57, 4656

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