Glycosaminoglycan synthesis is modulated by ciclesonide in human lung cells Source: Eur Respir J 2004; 24: Suppl. 48, 346s Year: 2004
Deposition and metabolism of inhaled ciclesonide in the human lung Source: Eur Respir J 2010; 36: 1113-1119 Year: 2010
Highly lipophilic fatty acid esters of the active metabolite of ciclesonide formed in vitro in rat lung tissue Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Uptake, retention and metabolism of ciclesonide in human alveolar epithelial cells Source: Eur Respir J 2005; 26: Suppl. 49, 255s Year: 2005
Unbound pharmacologically active metabolite des-CIC is not detectable in human skeletal muscle and subcutaneous adipose tissue after inhalation of high-dose ciclesonide Source: Eur Respir J 2006; 28: Suppl. 50, 666s Year: 2006
Investigation of the enzymatic hydrolysis of aclidinium bromide in human plasma Source: Annual Congress 2009 - New bronchodilators Year: 2009
Effects of zileuton on leukotriene formation in human blood cells and expression of enzymes in the biosynthetic pathway Source: Eur Respir J 2006; 28: Suppl. 50, 316s Year: 2006
Concentrations of ciclesonide and its metabolites in the human lung after inhalation of 1280 μg ciclesonide Source: Eur Respir J 2006; 28: Suppl. 50, 212s Year: 2006
Inhibition of human lung fibroblast functions by roflumilast N-oxide Source: Eur Respir J 2006; 28: Suppl. 50, 662s Year: 2006
Evidence of in vivo esterification of budesonide in humans Source: Eur Respir J 2005; 26: Suppl. 49, 370s Year: 2005
Different tissue accumulation kinetics of ciclesonide-active metabolite and budesonide in mice Source: Eur Respir J 2006; 28: Suppl. 50, 433s Year: 2006
Esterification prolongs retention of budesonide but not ciclesonide - active principle in rat trachea Source: Eur Respir J 2005; 26: Suppl. 49, 369s Year: 2005
Effects of ciclesonide (CIC) on human adult lung fibroblasts functions involved in airway inflammation and remodeling Source: Eur Respir J 2006; 28: Suppl. 50, 101s Year: 2006
Pronounced tissue and plasma protein binding of ciclesonide is responsible for reduced pharmacodynamic potency in the lung Source: Eur Respir J 2007; 30: Suppl. 51, 351s Year: 2007
The uptake of ciclesonide-active metabolite and budesonide into human hepatocytes in vitro – the effect of serum protein binding Source: Eur Respir J 2006; 28: Suppl. 50, 434s Year: 2006
PGD2 biosynthesis in several human mast cell models is catalyzed by cycloxygenase-1 Source: Annual Congress 2011 - Mechanisms of allergic inflammation of the airways Year: 2011
Tissue retention and esterification is greater for budesonide than for ciclesonide in trachea ex vivo Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Budesonide esterification in human bronchial epithelial cells is not impaired by formoterol Source: Eur Respir J 2002; 20: Suppl. 38, 619s Year: 2002
Tissue accumulation kinetics of ciclesonide-active metabolite and budesonide in mice Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD II Year: 2008
Exposure of human subcutaneous adipose tissue and skeletal muscle tissue to unbound active drug after inhalation of high-dose ciclesonide or budesonide Source: Eur Respir J 2007; 30: Suppl. 51, 351s Year: 2007