QGE031 high affinity anti-IgE: Tolerability, safety, pharmacokinetics and pharmacodynamics in atopic subjects

J. Arm, I. Bottoli, A. Skerjanec, A. Groenewegen, P. Lowe, S. Maahs (Cambridge, East Hanover, United States Of America; Basel, Switzerland)

Source: Annual Congress 2013 –Treatment of asthma
Session: Treatment of asthma
Session type: Oral Presentation
Number: 3537
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. Arm, I. Bottoli, A. Skerjanec, A. Groenewegen, P. Lowe, S. Maahs (Cambridge, East Hanover, United States Of America; Basel, Switzerland). QGE031 high affinity anti-IgE: Tolerability, safety, pharmacokinetics and pharmacodynamics in atopic subjects. Eur Respir J 2013; 42: Suppl. 57, 3537

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Safety, tolerability and pharmacokinetics of QAV680, an oral CRTh2 antagonist, in healthy subjects
Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology
Year: 2014


Safety profile and pharmacokinetics of SB010, an inhaled GATA-3-specific DNAzyme, in phase I clinical trials in healthy and asthmatic subjects
Source: Annual Congress 2013 –Emerging new targets for the treatment of respiratory diseases
Year: 2013

Safety, tolerability and pharmacokinetics of an oral competitive reversible CRTh2 antagonist, QAW039, in healthy subjects
Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology
Year: 2014


Efficacy of omalizumab in Polish real-world patients
Source: International Congress 2016 – Asthma management
Year: 2016


Safety and tolerability of acute dosing of beta-blockers in asthma
Source: Annual Congress 2013 –Asthma and COPD management: novel clinical findings
Year: 2013

LATE-BREAKING ABSTRACT: Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting the allergen-induced early asthmatic response
Source: International Congress 2014 – The future has started: emerging potentials for personalised asthma treatment
Year: 2014


Safety profile and pharmacokinetics of an inhaled GATA-3-specific DNAzyme in a phase Ib study in patients with stable allergic asthma
Source: Annual Congress 2013 –Emerging new targets for the treatment of respiratory diseases
Year: 2013

Efficacy and safety of fevipiprant (QAW039) in patients with atopic asthma uncontrolled on low-dose ICS therapy
Source: International Congress 2016 – Clinical and molecular studies in asthma
Year: 2016


Evaluating omalizumab persistency of response after long-term therapy (XPORT)
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014


P-PiXel: A ’real-life’ evaluation of omalizumab use in asthmatic patients
Source: International Congress 2016 – Asthma management
Year: 2016

Interim analysis of a prospective study investigating oral corticosteroid (OCS) use in omalizumab treated severe allergic asthma patients: APEX II study
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014


The impact of sublingual allergen-specific therapy on asthma control and quality of life
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014


A PKPD mathematical model to determine efficacy of multiple doses of QGE031 (ligelizumab) vs. omalizumab and placebo in inhibiting skin responses in atopic asthmatics
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015


Ultra-rush sublingual immunotherapy: Safety of use for patients with various allergic manifestations
Source: International Congress 2015 – Modulating the immune system in COPD and asthma
Year: 2015


Patterns of clinical use of omalizumab in Spain: A 5-year "real-life" study
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014


Tolerability and adherence to sublingual immunotherapy with mite vaccines with different schedule in asthmatic children
Source: International Congress 2014 – More paediatric asthma
Year: 2014

The clinical and genetic factors for predicting the response to inhaled corticosteroids
Source: International Congress 2014 – Biomarkers of asthma and clinical immunology
Year: 2014

Comparative efficacy of different groups of drugs for the treatment of bronchial asthma in combination with allergic rhinitis
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014

Abediterol: Efficacy, safety and tolerability of the novel LABA in patients with persistent asthma
Source: International Congress 2014 – Clinical trials of drugs for respiratory diseases
Year: 2014

Global evaluation of treatment effectiveness (GETE) is an accurate predictor of response to omalizumab in patients with severe allergic asthma: A pooled analysis
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014