Influenza infection of human lung macrophages increases PDL1 expression

K. J. Staples, B. Nicholas, C. M. Spalluto, R. T. McKendry, R. Djukanovic, T. M. A. Wilkinson (Southampton, United Kingdom)

Source: Annual Congress 2013 –Viral infections
Session: Viral infections
Session type: Poster Discussion
Number: 1883
Disease area: Respiratory infections

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
K. J. Staples, B. Nicholas, C. M. Spalluto, R. T. McKendry, R. Djukanovic, T. M. A. Wilkinson (Southampton, United Kingdom). Influenza infection of human lung macrophages increases PDL1 expression. Eur Respir J 2013; 42: Suppl. 57, 1883

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
LSC 2014 abstract - Influenza infection of human lung macrophages increases PDL1 expression via autologous IFNbeta
Source: International Congress 2014 – Immunology of respiratory infections
Year: 2014

Differential sensitivity of subsets of monocyte-derived macrophages to apoptosis; its impact on lung inflammation
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Fluticasone propionate reduces influenza infection of human macrophages
Source: International Congress 2015 – Infection in COPD: different aspects of the host/pathogen balance
Year: 2015


IL-33 and TSLP gene expression are increased in response to human rhinovirus 1B in HDM-treated murine bone marrow-derived macrophages
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Modulation of PD-1 and PD-L1 expression in response to acute viral infection of human lung tissue
Source: International Congress 2014 – Cell biology 2014
Year: 2014

IP-10 is selectively produced in the airways upon respiratory virus infection
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Induction of galectin-9 production by viral infection in the lung
Source: International Congress 2015 – The multiple faces of host defense
Year: 2015

RSV infection modulates IL-15 production and MICA levels in respiratory epithelial cells
Source: Eur Respir J 2012; 39: 712-720
Year: 2012



Adiponectin acts as an anti-inflammatory cytokine on human lung macrophages
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Characterization of M1 and M2 macrophages in human lung tissue
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Effect of JQ-1 on monocyte-derived macrophage (MDM) phagocytosis of bacteria and cytokine release
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Attenuated lymphocyte immune response in mycobacterium avium complex-lung disease through over-expressed programmed death-1 receptor
Source: International Congress 2016 – Clinical and microbiological aspects of bronchiectasis and non-tuberculous mycobacterium (NTM) infections
Year: 2016

Biomass smoke particles induce cytokines and reduce phagocytosis by monocyte-derived macrophages
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Alpha-1-antitrypsin regulates IL-8 release and CXCR2 expression in human neutrophils
Source: International Congress 2014 – Cells, biofilms and biomarkers in respiratory infections
Year: 2014

Expression of the B cell differentiation factor BAFF and chemokine CXCL13 in a murine model of human respiratory syncytial virus infection
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Migration of human monocytes is stimulated by Jagged-1 and DLL-4 via the notch pathway
Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology
Year: 2014

Phenotypes of alveolar macrophages in normal human lung and their polarization with disease
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014

Role of 15-lipoxygenase in the polarization of human lung macrophages
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Viral infection of macrophages reduces CD36 expression: Implications for phagocytosis of non-typeable haemophilus influenzae
Source: International Congress 2015 – Viral infections: basic research and clinical perspective
Year: 2015

Impact of IL-13 on RSV infection in vitro and in vivo
Source: Annual Congress 2013 –Viral infections
Year: 2013