A protease inhibitor from the tick rhipicephalus boophilus microplus attenuated parenchymal destruction in elastase-induced emphysema

C. Rosa Olivo, J. Dias Lourenço, F. M. Almeida, L. Paiva Neves, P. Mello Arantes, C. Máximo Prado, I. Tibério, A. S. Tanaka, S. D. Sasaki, M. Arruda Martins, F. DTQS Lopes (Sao Paulo, Diadema, Santo Andre, Brazil)

Source: Annual Congress 2013 –Novel mechanisms in lung injury
Session: Novel mechanisms in lung injury
Session type: Thematic Poster Session
Number: 667
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. Rosa Olivo, J. Dias Lourenço, F. M. Almeida, L. Paiva Neves, P. Mello Arantes, C. Máximo Prado, I. Tibério, A. S. Tanaka, S. D. Sasaki, M. Arruda Martins, F. DTQS Lopes (Sao Paulo, Diadema, Santo Andre, Brazil). A protease inhibitor from the tick rhipicephalus boophilus microplus attenuated parenchymal destruction in elastase-induced emphysema. Eur Respir J 2013; 42: Suppl. 57, 667

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effects of a protease inhibitor from the tick rhipicephalus boophilus microplus in an experimental model of emphysema
Source: Annual Congress 2011 - Recent developments in COPD
Year: 2011


Plant proteinase inhibitor from crataeva tapia (CrataBl) attenuates inflammation and remodelling induced by elastase in mice
Source: Annual Congress 2013 –Novel mechanisms in lung injury
Year: 2013

BmTI-A: A serine protease inhibitor attenuates hyperresponsiveness in an experimental model of chronic allergic inflammation in Balb/c mice
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014

BmTI-A, a serine protease inhibitor, reduces the chronic allergic lung inflammation in a mice model
Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis
Year: 2015

Plant proteinase from bauhinia bauhinioides kallikrein inhibitor (BbKI) attenuates inflammation and remodelling induced by elastase in mice
Source: International Congress 2014 – Novel evidence relating to respiratory treatment development
Year: 2014

Plant proteinase from bauhinia bauhinioides kallikrein inhibitor (BbKI) attenuates inflammation and remodelling induced by elastase in mice
Source: Annual Congress 2013 –Novel mechanisms in lung injury
Year: 2013

Galectin-9 attenuates elastase-induced emphysema by reducing neutrophil chemotaxis in mice
Source: International Congress 2016 – New signalling pathways in COPD
Year: 2016

Plant proteinase inhibitor from bauhinia bauhinioides attenuates elastase-induced emphysema in mice
Source: Annual Congress 2010 - Novel cellular mechanisms in lung disease
Year: 2010


Treatment with Syk inhibitors after establishment of disease phenotype in a chronic HDM model of allergic airways inflammation abolishes AHR and attenuates inflammatory mediator expression
Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD
Year: 2015

A novel non-human primate model of cigarette smoke-induced chronic obstructive pulmonary disease
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014

House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
Source: Eur Respir J 2010; 35: 1377-1387
Year: 2010



Effects of phosphoinositide-3-kinase inhibitors on steroid-insensitive airway inflammation in poly(I:C) and allergen challenged mice
Source: International Congress 2016 – Novel mechanisms and treatment modalities in asthma
Year: 2016


Viral mimetic Poly(I:C) exacerbates cigarette smoke-induced pulmonary inflammation by facilitating the release of neutrophil-derived elastase
Source: International Congress 2014 – Mechanisms of COPD and inhalation injury
Year: 2014


Peptide ToAP3 from T. obscurus interferes with idiopathic pulmonary fibrosis progression in murine model.
Source: International Congress 2019 – Immune-mediated interstitial lung diseases: from bench to bedside
Year: 2019

Type II transmembrane serine protease matriptase is a mediator of pulmonary fibrosis
Source: Annual Congress 2013 –Translational studies in chronic repair and remodelling in the lung
Year: 2013


Treatment with proteinase inhibitor, BbCI, modulates inflammatory response, mechanic alterations, and remodeling on elastase-induced emphysema in mice
Source: Annual Congress 2012 - The many roads to lung injury
Year: 2012

Effectiveness of 15-deoxy-delta-12-14-prostaglandin J2 on established asthma pathological changes triggered by house dust mite in mice
Source: International Congress 2015 – Novel targets and strategies for the treatment of cough, asthma, rhinosinusitis and COPD
Year: 2015



Plant proteinase inhibitor from enterolobium contortisiliquum (EcTI) attenuates elastase-induced pulmonary inflammatory and remodeling alterations in mice
Source: Annual Congress 2011 - Recent developments in COPD
Year: 2011


Metalloproteases gene expression and remodeling of lung parenchyma fibers during the progression of elastase induced emphysema
Source: International Congress 2014 – Mechanisms of COPD and inhalation injury
Year: 2014