The PDE4 inhibitor roflumilast reduced bleomycin-induced pulmonary fibrotic and vascular remodeling in mice in vivo Source: Annual Congress 2008 - Animal models of pulmonary fibrosis: mechanisms and therapies Year: 2008
Inhibition of cytokine release from alveolar macrophages in sarcoidosis by pentoxifylline: comparison with dexamethasone Source: Eur Respir J 2001; 18: Suppl. 33, 195s Year: 2001
A neutrophil elastase inhibitor prevents bleomycin-induced pulmonary fibrosis in mice Source: Eur Respir J 2012; 40: 1475-1482 Year: 2012
Roflumilast potently inhibits CXCL1 mediated neutrophil migration in COPD patients Source: Annual Congress 2011 - COPD: clinical studies and animal cell models Year: 2011
Effect of roflumilast on LPS-induced influx of inflammatory cells in lungs of healthy subjects Source: Eur Respir J 2006; 28: Suppl. 50, 436s Year: 2006
Rolipram, a PDE4 inhibitor, but not prednisolone, inhibited pulmonary neutrophilia induced by intratracheal instillation of IL-8 in mice Source: Eur Respir J 2005; 26: Suppl. 49, 104s Year: 2005
Pentoxifylline inhibits the neutrophil alveolitis in a murine ARDS model Source: Eur Respir J 2001; 18: Suppl. 33, 238s Year: 2001
Inhibition of neutrophil elastase contributes to attenuationof lipopolysaccharide-induced acute lung injuryduring neutropenia recovery in mice Source: International Congress 2017 – Anti-inflammatory and pro-repair mediators in acute lung injury Year: 2017
LATE-BREAKING ABSTRACT: Roflumilast and its active metabolite inhibit LPS-induced cytokines production from human parenchymal and bronchial explants: interaction with formoterol Source: Annual Congress 2009 - Airway cell biology Year: 2009
SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects Source: Eur Respir J 2010; 35: 564-570 Year: 2010
Inhibition of LPS-induced cytokine/chemokine production from human lung macrophages by roflumilast is enabled by autocrine PGE2 Source: Annual Congress 2010 - Macrophages: cell biology and disease-specific characteristics Year: 2010
Effect of neutrophil elastase inhibitor on airway inflammation and airway hyperresponsiveness in a murine model of asthma Source: Annual Congress 2009 - Animal models of airways inflammation Year: 2009
The selective phosphodiesterase 4 inhibitor, cilomilast, inhibits interleukin-8-induced pulmonary neutrophil accumulation in the rabbit Source: Eur Respir J 2001; 18: Suppl. 33, 35s Year: 2001
Roflumilast inhibits chemokine release in animal models of COPD and asthma Source: Eur Respir J 2004; 24: Suppl. 48, 690s Year: 2004
Effects of corticosteroid or montelukast associated to iNOS inhibition on inflammation and remodelling of distal lung in animals with chronic inflammation Source: Annual Congress 2010 - Models of airways disease Year: 2010
Effect of curcumin on LPS-induced neutrophil activation and acute lung injury Source: Annual Congress 2012 - Lung injury, respiratory muscles and mechanical ventilation Year: 2012
The novel phosphodiesterase 4 inhibitor CI-1044 inhibits in vitro LPS-induced TNFα production in whole blood of COPD patients Source: Eur Respir J 2001; 18: Suppl. 33, 34s Year: 2001
Effects of a neutrophil elastase inhibitor against mediators of acute exacerbation of pulmonary fibrosis: a new therapeutic strategy Source: Annual Congress 2008 - New therapeutic strategies in idiopathic pulmonary fibrosis Year: 2008
Inhaled CCR1 antagonist AZD4818 reduces leucocyte influx in the rat lipopolysaccharide (LPS) lung inflammation model Source: Annual Congress 2009 - Preclinical models in drug development Year: 2009
The effect of pentoxifylline on IL-12 and IL-18 release by alveolar macrophages in sarcoidosis and hypersensitivity pneumonitis versus idiopathic pulmonary fibrosis Source: Eur Respir J 2003; 22: Suppl. 45, 377s Year: 2003