Impaired muscle mitochondrial density and/or function: a COPD-specific mitochondropathy or simply deconditioning?

Aili L. Lazaar, Paul L. Greenhaff

Source: Eur Respir J 2012; 40: 1070-1071
Journal Issue: November
Disease area: Airway diseases

Full text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Aili L. Lazaar, Paul L. Greenhaff. Impaired muscle mitochondrial density and/or function: a COPD-specific mitochondropathy or simply deconditioning?. Eur Respir J 2012; 40: 1070-1071

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Mitochondrial functional alterations in COPD locomotor muscle are independent of cachexia and fiber type shift
Source: International Congress 2014 – Pathophysiological mechanisms at different scales
Year: 2014

Intrinsic mitochondrial function in COPD is not impaired in lower limb skeletal muscle
Source: International Congress 2016 – From cardiopulmonary interaction to locomotor muscles and dyspnoea in health and disease
Year: 2016

Muscle morphology, metabolism and muscle function: general principles
Source: ISSN=1025-448x, ISBN=1-904097-27-8, page=86
Year: 2003

Mitochondrial dysfunction in COPD patients with low body mass index
Source: Eur Respir J 2007; 29: 643-650
Year: 2007



Does daily activity affect forearm muscle energy metabolism in patients with chronic respiratory impairment?
Source: Eur Respir J 2004; 24: Suppl. 48, 215s
Year: 2004

Decreased muscle PPAR concentrations: a mechanism underlying skeletal muscle abnormalities in COPD?
Source: Eur Respir J 2007; 30: 191-193
Year: 2007


Oxidative DNA damage and mitochondrial DNA depletion in COPD locomotor muscle
Source: International Congress 2014 – Clinical physiology and respiratory muscles
Year: 2014

Exercise capacity, peripheral muscle strength, and balance are related in primary ciliary dyskinesia
Source: Virtual Congress 2021 – Peripheral muscle function, exercise capacity and functional status in respiratory disease
Year: 2021


Does physical activity affect respiratory muscle strength?
Source: International Congress 2016 – What's new in paediatric respiratory physiology?
Year: 2016


Capillary density of the quadriceps in COPD patients: an structural determinant of muscle endurance?
Source: Eur Respir J 2003; 22: Suppl. 45, 573s
Year: 2003

Lung function, functional capacity, energy cost, and nutritional status in cystic fibrosis with and without inspiratory muscle weakness
Source: International Congress 2019 – New views on testing and training of respiratory muscles
Year: 2019

Role of skeletal muscle dysfunction in the deterioration  of life quality in patients with COPD
Source: International Congress 2017 – Extrapulmonary comorbidities in COPD
Year: 2017


Assessment of muscle function
Source: School Course 2012 - Practical Issues in Pulmonary Rehabilitation
Year: 2012



Impaired myogenesis in the quadriceps muscle of cachectic COPD patients
Source: International Congress 2014 – Respiratory pathophysiology: mechanisms of alteration of lung, respiratory and peripheral muscle function
Year: 2014


Gender differences in COPD patients: Skeletal muscle function and structure
Source: Annual Congress 2013 –Guidelines and exacerbations
Year: 2013

The respiratory muscle pump: peripheral function
Source: International Consensus Conference in Intensive Care Medicine 2005
Year: 2005


Impaired coordination of skeletal muscle protein turnover signalling in sarcopenic COPD patients
Source: International Congress 2016 – How the understanding og molecular and genomic crosstalk is helping to diagnose lung disease
Year: 2016

Staging of COPD without respect of body composition underestimates muscle wasting-associated impaired functional performance
Source: Eur Respir J 2001; 18: Suppl. 33, 488s
Year: 2001

Assessment of respiratory muscle function
Source: ERS Course 2020 - Pulmonary rehabilitation
Year: 2020


The relationships between functional exercise capacity, respiratory muscle strength, peripheral muscle strength and endurance in patients with metabolic syndrome
Source: Annual Congress 2013 –Assessment methods involved in the physiotherapy treatment in different patient populations
Year: 2013