Protease activated receptor-1 (PAR-1) stimulation leads to αvβ6 integrin mediated TGFβ activation via rho kinase Source: Eur Respir J 2005; 26: Suppl. 49, 238s Year: 2005
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
Thrombin activates mitogen activated protein (MAP) kinase and activated protein-1 (AP-1) to induce interleukin-8 (IL-8) release from airway epithelial cells Source: Annual Congress 2003 - Mechanisms of lung injury: from bench to bedside Year: 2003
Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008
TNF-α inhibits human eosinophil apoptosis by activating p55 receptor and NF-κB Source: Eur Respir J 2001; 18: Suppl. 33, 162s Year: 2001
Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 571s Year: 2002
Neutrophil elastase causes MUC5AC mucin synthesis via a EGF receptor, ERK and NF-kB pathway in A549 cells Source: Eur Respir J 2004; 24: Suppl. 48, 554s Year: 2004
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
Human rhinovirus induces the expression of the membrane bound form of its cellular receptor intercellular adhesion molecule 1via a tyrosine kinase dependent signal transduction pathway Source: Eur Respir J 2001; 18: Suppl. 33, 160s Year: 2001
LSC 2011 Abstract: P2Y2 receptor regulates VCAM-1 membrane and soluble forms and eosinophil accumulation during lung inflammation Source: Annual Congress 2011 - Experimental modulation of airway inflammation Year: 2011
Proteinase-activated receptor-2 (PAR2 ) activation on human lung fibroblasts increases IL-6 & IL-8 mRNA expression Source: Annual Congress 2003 - Mechanisms of lung injury: from bench to bedside Year: 2003
Transforming growth factor-α (TGF-α)-induced interleukin-8 (IL-8) release in human bronchial epithelial cells in vitro: role of mitogen-activated protein kinases (MAPK) Source: Eur Respir J 2002; 20: Suppl. 38, 573s Year: 2002
Endotoxin induces proliferation of NSCLC cells by a COX-2 dependent manner – Role of CD14, TLRs and EGFR signaling Source: Annual Congress 2010 - Pathology of lung cancer Year: 2010
Regulation of cytokine- and phorbol ester-mediated interleukin (IL)-8 expression in the absence or presence of pyocyanin in human bronchial epithelial cell line: roles of protein kinase C and mitogen-activated protein kinases Source: Eur Respir J 2005; 26: Suppl. 49, 99s Year: 2005
G-protein mediated EGFR transactivation induces mucin production Source: Annual Congress 2003 - Cellular and molecular mechanisms in epithelium injury and repair Year: 2003
Transforming growth factor-β inhibition of lung fibroblast proliferation is mediated through prostaglandin E2 , via activation of p38 mitogen-activated protein kinase Source: Annual Congress 2005 - Pulmonary hypertension and fibrosis: novel mechanisms Year: 2005
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils Source: Eur Respir J 2003; 22: Suppl. 45, 548s Year: 2003