Relationship of resting lung volume status and dynamic hyperinflation during exercise in the patients with chronic airflow limitation

S. J. Kim, W. S. Kim (Seoul, South Korea)

Source: Annual Congress 2003 - Respiratory structure and mechanisms: current concepts
Session: Respiratory structure and mechanisms: current concepts
Session type: Oral Presentation
Number: 165
Disease area: Airway diseases

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Abstract

Dynamic hyperinflation is an important mechanism lead to exercise limitation in the patients with chronic airflow limitation (CAL). CAL actually appears in various disease states as well as COPD. So, the patients with CAL show quite differences in the resting lung volume status according to their disease state although similar degree of expiratory flow limitation represented as FEV1. We studied about the relationship of resting lung volume status and dynamic hyperinflation during exercise. In 27 patients with chronic airflow limitation resulted from various causes, We examined baseline dyspnea index, spirometry and lung volume at rest, and assessed dynamic hyperinflation from inspiratory capacity (IC) measurement by IC maneuver during constant load exercise. The degree of dynamic hyperinflation during exercise test showed correlation with the total lung capacity (r=0.45, p= 0.01). In comparison of the differences in dynamic hyperinflation between two groups according to relative lung volume status, the group with relatively higher resting lung volume showed much degree of dynamic hyperinflation (6.5±10.1% vs. 0.1±4.8%, p=0.04) and a worse tendency of baseline dyspnea index (7.8±1.7 vs. 9.0±1.3, p=0.051) than the group with relatively lower lung volume. In the patients with CAL, the patients with the lower resting lung volume develop lesser degree of dynamic hyperinflation during exercise and dyspnea on exercise than the patients with the higher resting lung volume.
Key words: chronic airflow limitation, exercise limitation, lung volume, dynamic hyperinflation


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S. J. Kim, W. S. Kim (Seoul, South Korea). Relationship of resting lung volume status and dynamic hyperinflation during exercise in the patients with chronic airflow limitation. Eur Respir J 2003; 22: Suppl. 45, 165

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