Protective effects of hypercapnic acidosis on endotoxin-induced endothelial cell injury

K. Takeshita, Y. Suzuki, M. Ishii, N. Miyao, H. Kudo, R. Hiraoka, K. Nishio, T. Aoki, K. Yamaguchi (Minato-ku, Shinjuku-ku, Japan)

Source: Annual Congress 2004 - Translation of lung inflammation from bench to bedside
Session: Translation of lung inflammation from bench to bedside
Session type: Poster Discussion
Number: 4415
Disease area: Airway diseases, Pulmonary vascular diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
K. Takeshita, Y. Suzuki, M. Ishii, N. Miyao, H. Kudo, R. Hiraoka, K. Nishio, T. Aoki, K. Yamaguchi (Minato-ku, Shinjuku-ku, Japan). Protective effects of hypercapnic acidosis on endotoxin-induced endothelial cell injury. Eur Respir J 2004; 24: Suppl. 48, 4415

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Protective effect of Polydexyribonucleotide against lipopolysaccharide-induced acute lung injury in rats
Source: International Congress 2017 – From respiratory muscles to acute respiratory failure
Year: 2017


Does hypercapnia and respiratory acidosis have protective effect in a ventilator-induced lung injury model?
Source: Eur Respir J 2005; 26: Suppl. 49, 559s
Year: 2005

Therapeutic effect of hypothermia on endotoxin-induced acute lung injury in rats
Source: Eur Respir J 2004; 24: Suppl. 48, 265s
Year: 2004

Mechanisms of vascular endothelial cell injury in response to intermittent and continuous hypoxia exposure and protective effects of anti-inflammatory and anti-oxidant agents
Source: International Congress 2019 – Novel methods, diagnostics and biomarkers in chronic lung diseases
Year: 2019

Protective effects of peroxiredoxin 6 on lipopolysaccharide-induced acute lung injury
Source: Annual Congress 2009 - Crossing the line: alveolo-capillary barrier control in acute lung injury
Year: 2009

Buffering of the acidosis induced by hypercapnia modulates the inflammatory process in lung and distal organs in experimental acute lung injury
Source: Annual Congress 2009 - Acute lung injury: biological mechanisms
Year: 2009



Prevention of hyperoxia-induced lung injury: Counterbalancing the deleterious effects of endothelin-1 in rat lungs
Source: Annual Congress 2012 - Lung injury and repair: reactive oxygen species and beyond
Year: 2012

Creatine supplementation attenuates systemic and pulmonary effects of acute lung injury induced by pulmonary ischemia-reperfusion in rats
Source: Annual Congress 2012 - Lung transplantation: studies in candidates and recipients
Year: 2012


Protective effects of keratinocyte growth factor-2 on lipopolysacchride-induced acute lung injury
Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis
Year: 2010

Effects of N-acetylcysteine in lipopolysaccharide-induced acute lung injury in the rat: Treatment after acute lung injury
Source: Annual Congress 2011 - Mechanical ventilation and lung injury: new advances
Year: 2011

Protective role of carbon monoxide treatment in porcine endotoxin-induced acute lung injury
Source: Eur Respir J 2007; 30: Suppl. 51, 407s
Year: 2007

Pioglitazone attenuates endotoxin-induced acute lung injury by reducing neutrophil recruitment
Source: Eur Respir J 2012; 40: 416-423
Year: 2012



Lung damage in chronic hypoxic rats and antagonistic effects of aminophylline on the damage
Source: Annual Congress 2008 - Pathophysiology of respiratory diseases
Year: 2008


Ghrelin attenuates lipopolysaccharide-induced acute lung injury
Source: Eur Respir J 2005; 26: Suppl. 49, 731s
Year: 2005

Heparin decreases permeability of microvascular endothelium in rats with hypobaric and hypertension-induced chronic hypoxia
Source: Eur Respir J 2002; 20: Suppl. 38, 89s
Year: 2002

Endothelial- but not leukocytic-NOX2 mediates vascular injury in ischemia/reperfusion syndrome of the lung
Source: Eur Respir J 2006; 28: Suppl. 50, 822s
Year: 2006

Hypoxia aggravates  failure of autoresuscitation  in a rat model of LPS-induced endotoxemia.
Source: International Congress 2018 – Preclinical and clinical studies of critical illness
Year: 2018

The protective effects of paricalcitol on renal ischemia reperfusion induced lung injury
Source: International Congress 2018 – Triggers of acute lung injury: mechanical ventilation and oxygen levels
Year: 2018

Creatine supplementation inhibits acute lung injury induced by pulmonary ischemia-reperfusion
Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis
Year: 2010


Effect of curcumin on LPS-induced neutrophil activation and acute lung injury
Source: Annual Congress 2012 - Lung injury, respiratory muscles and mechanical ventilation
Year: 2012