Erythropoietin (EPO) attenuates the expression of its receptor (EPO-R) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats

D. Tsavlis, A. Tzoumaka, G. Kokaraki, K. Kouzi-Koliakou, A. Tektonidou, A. Papadopoulou, E. Spandou (Thessaloniki, Greece)

Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Session: Fibrogenesis between epithelial injury and fibroblast proliferation
Session type: Thematic Poster Session
Number: 3753
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
D. Tsavlis, A. Tzoumaka, G. Kokaraki, K. Kouzi-Koliakou, A. Tektonidou, A. Papadopoulou, E. Spandou (Thessaloniki, Greece). Erythropoietin (EPO) attenuates the expression of its receptor (EPO-R) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats. Eur Respir J 2012; 40: Suppl. 56, 3753

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Erythropoietin (EPO) attenuates the immunohistochemical expression of tumor growth factor-ß (TGF-ß) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: International Congress 2018 – Pulmonary fibrosis: from models to patients
Year: 2018

Erythropoietin (EPO) attenuates the immunohistochemical expression of autophagy antibodies in bleomycin (BLM), induced pulmonary fibrosis (PF) in rats
Source: International Congress 2019 – New mechanistic insights into pulmonary fibrosis
Year: 2019

Erythropoietin (EPO) inhibits the bleomycin (BLM)-induced pulmonary fibrosis in rats
Source: Annual Congress 2010 - Emerging mechanisms in lung injury
Year: 2010

The effect of erythropoietin (EPO) on cyclooxygenase-2 (COX-2) and cytochrome-c (CYT-c) in the bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: Annual Congress 2011 - The ageing pulmonary interstitium
Year: 2011

Erythropoietin (EPO) inhibits the immunohistochemical expression of lysyl oxidase (LOX) in bleomycin (BLM)-induced pulmonary fibrosis (PF) in rats
Source: International Congress 2015 – Pulmonary fibrosis: mechanisms of disease
Year: 2015

Hepatocyte growth factor (HGF) expression in bronchoveolar lower (BAL) does not confirm its anti-fibrotic activity in interstitial lung diseases (ILD)
Source: Annual Congress 2012 - Idiopathic pulmonary fibrosis
Year: 2012

The attenuating effect of erythropoietin (EPO) on the expression of myeloperoxidase (MPO) in bleomycin-induced pulmonary fibrosis in rats
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013

Longterm treatment effects of pulmonary hypertantion (PH) in idiopathic pulmonary fibrosis (IPF) patients by endothelin receptor blockade (Bosentan)
Source: Eur Respir J 2007; 30: Suppl. 51, 120s
Year: 2007

Upregulation of interleukin 13 receptor alpha 2 (IL-13RA2) expression in idiopathic pulmonary fibrosis
Source: Eur Respir J 2005; 26: Suppl. 49, 267s
Year: 2005

Post-treatment with the heat shock protein 90 (hsp90) inhibitor, AUY-922, reduces lung hsp90 tyrosine (Y) phosphorylation and pulmonary inflammation in LPS-induced acute lung injury (ALI) in mice
Source: Annual Congress 2013 –The role of hormones and cytokines in lung injury
Year: 2013

LSC Abstract – Toll-like receptor 4 (TLR4) in idiopathic pulmonary fibrosis (IPF)
Source: International Congress 2015 – IPF pathogenesis
Year: 2015



Endothelin receptor antagonist (ETRA) bosentan (B) in patients with severe pulmonary hypertension (PH) associated with pulmonary disease
Source: Annual Congress 2010 - Pulmonary circulation II
Year: 2010

Expression of insulin-growth factor-I (IGF-I) in alveolar lymphocytes (AL) in interstitial lung diseases (ILD). Potential functions of AL-derived IGF
Source: Annual Congress 2005 - Progresses in lung fibrosis
Year: 2005


Glucocorticosteroid receptor (GCR) gene isoforms expression in bronchial asthma (BA) patients
Source: Annual Congress 2011 - Asthma: a heterogeneous disease
Year: 2011


Endothelin receptor B (ETBR) dependent GM-CSF mRNA stabilization explains the higher efficacy of bosentan vs. ambrisentan in the reduction of GM-CSF release from human airway smooth muscle cells (HASMCs)
Source: Annual Congress 2011 - Experimental modulation of airway inflammation
Year: 2011

Elevated integrin ?5 expression in idiopathic pulmonary fibrosis (IPF) derived fibroblasts is linked to paracrine TNF-a signaling
Source: International Congress 2017 – Cellular signalling pathways in pulmonary fibrosis
Year: 2017

Expression of transforming growth factor β (TGFβ) receptor, CD105, is declined in Th1 interstitial lung diseases (ILDs)
Source: Annual Congress 2011 - Bronchoalveolar lavage and biomarkers in diffuse parenchymal lung disease
Year: 2011


Regulation, cell-specific expression and metabolism of factor VII activating protease (FSAP) in lungs from patients with acute respiratory distress syndrome (ARDS) and idiopathic pulmonary fibrosis (IPF)
Source: Eur Respir J 2006; 28: Suppl. 50, 823s
Year: 2006

Fractalkine and its receptor (CX3CR1) in primary pulmonary hypertension (PPH)
Source: Eur Respir J 2001; 18: Suppl. 33, 2s
Year: 2001

Expression of bradykinin B2 receptor (B2R) and vascular endothelial growth factor (VEGF) in asthma and COPD
Source: Eur Respir J 2007; 30: Suppl. 51, 138s
Year: 2007