BMP-Smad1 target gene Wnt inhibitory factor 1 (WIF1) coordinates BMP and Wnt signaling activities in regulating lung development in vivo Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases Year: 2010
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Enhanced efficiency of phenotypic transition of asthmatic fibroblasts depends on canonical and non-canonical TGFß/Smad signaling pathways Source: International Congress 2018 – Identification of therapeutic targets for asthma Year: 2018
Activation of WNT co-receptor LRP5 is required for WNT and TGF-ß1 induced fibroblast activation Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies Year: 2020
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
DTX3L mediated regulation of TBK1 positively regulates type I IFN signalingpathway and cellular antiviral response Source: Virtual Congress 2020 – Different aspects of paediatric viral and bacterial lung infections Year: 2020
G-protein mediated EGFR transactivation induces mucin production Source: Annual Congress 2003 - Cellular and molecular mechanisms in epithelium injury and repair Year: 2003
Analysis of cytokine signaling pathway JAK-STAT through their activation in patients with asthma Source: Annual Congress 2008 - Novel mechanisms and targets of molecular pulmonary pathology Year: 2008
Increased activation of TGF beta signal transduction via Smad2/3 in the airways of mice lacking T-bet Source: Eur Respir J 2002; 20: Suppl. 38, 1s Year: 2002
Human rhinovirus induces the expression of the membrane bound form of its cellular receptor intercellular adhesion molecule 1via a tyrosine kinase dependent signal transduction pathway Source: Eur Respir J 2001; 18: Suppl. 33, 160s Year: 2001
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Effects of surfactant protein A on proximal IκB-α/NF-κB signal transduction pathways Source: Eur Respir J 2005; 26: Suppl. 49, 552s Year: 2005
Live cell imaging of Smad2 and Smad3 signal transduction in response to TGF-beta Source: Eur Respir J 2004; 24: Suppl. 48, 455s Year: 2004
Glutathione redox regulates TGF-β-induced Smad activation and fibrogenic effect in human airway Source: Eur Respir J 2007; 30: Suppl. 51, 496s Year: 2007
PM2.5 induces EMT event by activating Notch pathway in vivo and vitro Source: International Congress 2019 – Diagnostic procedures and biology of lung cancer Year: 2019
Induced sputum differential gene expression implicates increased p38 signalling activity in severe asthma Source: Annual Congress 2011 - Molecular: pathology of infectious and inflammatory lung disease Year: 2011
Muscarinic receptor stimulation differentially regulates extracellular matrix gene expression in lung fibroblasts Source: Annual Congress 2011 - The ageing pulmonary interstitium Year: 2011
GATA-3 phosphorylation by p38 MAP kinase plays a critical role in regulating Th2 cytokine gene expression Source: Eur Respir J 2003; 22: Suppl. 45, 386s Year: 2003
Temporal analysis of the intracellular signaling pathways involved in Th17/Treg response in COPD development Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD Year: 2019