Synergistic therapy for NSCLC: Additive preclinical efficacy of interleukin-6 inhibitor madindoline A with crizotinib

H. Ge, S. Ni, X. Fang, N. Xu, Y. Liu, Y. Song, C. Bai (Shanghai, Nantong, China)

Source: Annual Congress 2012 - Treatment of lung cancer
Session: Treatment of lung cancer
Session type: Poster Discussion
Number: 2912
Disease area: Thoracic oncology

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
H. Ge, S. Ni, X. Fang, N. Xu, Y. Liu, Y. Song, C. Bai (Shanghai, Nantong, China). Synergistic therapy for NSCLC: Additive preclinical efficacy of interleukin-6 inhibitor madindoline A with crizotinib. Eur Respir J 2012; 40: Suppl. 56, 2912

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Synergistic anti-tumor effects of vandetanib, an inhibitor of VEGFR and EGFR tyrosine kinase inhibitor, combined with cytotoxic agents in lung cancer cell lines
Source: Annual Congress 2010 - Treatment of lung cancer
Year: 2010

Novel anti-angiogenic pharmacotherapy strategies
Source: Annual Congress 2005 - Update on the role of angiogenesis in the pathogenesis and treatment of lung diseases
Year: 2005

Emerging prognostic biomarkers in non small cell lung cancer patients: Impact of treatment with nimesulide (COX-2 inhibitor) combined with chemotherapy
Source: Annual Congress 2011 - Biomarkers and other new methods for lung cancer
Year: 2011


Combination therapy of gefitinib and CYP3A4 inhibitor on non-small-cell lung cancer patients with an EGFR mutation and carcinomatous meningitis
Source: Annual Congress 2010 - Treatment of lung cancer
Year: 2010

Late Breaking Abstract - Randomized phase III study of erlotinib compared to intercalated erlotinib with cisplatin and pemetrexed as first-line therapy for advanced EGFR mutated non-small cell lung cancer, the NVALT 17 study.
Source: Virtual Congress 2021 – New clinical and biological developments in lung cancer
Year: 2021



Targeting of STAT3 and survivin with TG101209, a novel JAK2 inhibitor, enhances radiotherapy in lung cancer models
Source: Annual Congress 2010 - New insights in the pathology of lung cancer
Year: 2010

Cost-effectiveness of afatinib versus erlotinib for the treatment of squamous non-small cell lung cancer in france after a first-line platinum based therapy
Source: International Congress 2017 – Does economisation of medicine transfer into benefits for patients?
Year: 2017


Short-term efficacy of advanced NSCLC patients receiving anlotinib hydrochloride as the first and second-line treatment
Source: Virtual Congress 2020 – Prognostic and predictive factors: treatment of lung cancer
Year: 2020

Cost-effectiveness of three strategies for second-line erlotinib initiation in nonsmall-cell lung cancer: the ERMETIC study part 3
Source: Eur Respir J 2012; 39: 172-179
Year: 2012



Cost-effectiveness of three strategies for second-line erlotinib initiation in nonsmall-cell lung cancer: the ERMETIC study part 3
Source: Eur Respir J 2011; 39: 172-179
Year: 2012



Phase I trial of pemetrexed, carboplatin and sorafenib as first-line treatment in patients with metastatic NSCLC
Source: Annual Congress 2010 - Treatment of lung cancer
Year: 2010

Role of anlotinib-induced CCL2 decrease in anti-angiogenesis and response prediction for nonsmall cell lung cancer therapy
Source: Eur Respir J, 53 (3) 1801562; 10.1183/13993003.01562-2018
Year: 2019



Maintenance treatment with erlotinib after induction chemotherapy for advanced NSCLC
Source: Annual Congress 2011 - Recent therapeutic advances with tyrosine-kinase inhibitors in nonsmall-cell lung cancer
Year: 2011


Comparison of in-vitro anti-fibrotic effects of pirfenidone and nintedanib
Source: International Congress 2019 – Translational aspects of idiopathic interstitial pneumonia
Year: 2019

Better quality-of-life in patients with exon 19 deletion receiving first-line tyrosine kinase inhibitors for advanced non-small-cell lung cancer
Source: International Congress 2017 – Noteworthy lung cancer patient reports: reported outcome measures, smoking cessation, weight and sleep disorders
Year: 2017

The role of somatostatin analogues in combination to antineoplastic agents in the treatment of SCLC patients (preliminary findings)
Source: Annual Congress 2009 - Management of thoracic malignancies
Year: 2009


Efficacy and prognostic factors of first-line afatinib treatment for the EGFR-mutated non-small cell lung cancer in the real world
Source: Virtual Congress 2020 – Real-world data and registries of thoracic oncology
Year: 2020

Potential therapeutic significance of CIK cells in gefitinib resistant NSCLC with EGFR mutations
Source: Annual Congress 2011 - Progress in pathology of lung cancer
Year: 2011


Phase II study of gemcitabine plus irinotecan as second-line chemotherapy in advanced non-small cell lung cancer
Source: Annual Congress 2009 - Management of thoracic malignancies
Year: 2009

Phase II open-label study to investigate efficacy and safety of PTK787/ZK 222584 (PTK/ZK) orally administered once daily at 1250 mg as second-line monotherapy in patients (pts) with stage IIIB/IV non-small-cell lung cancer (NSCLC)
Source: Annual Congress 2006 - Lung cancer treatment
Year: 2006