Source: Annual Congress 2004 - New developments in endobronchial treatment
Disease area: Thoracic oncology

Abstract

Objectives: In the field of endobronchial recanalization procedures, endobronchial cryorecanalization is an new method to extract endobronchial tumors. It differs from conventional cryotherapy. A cryoprobe with increased cooling capacitiy and tensile strength was used here. The method was already shown to be effective. Collecting increased numbers of patients treated, the method has still to be evaluated in terms of safety and efficacy. This study shows the results of an increased number of interventions performed with this technique.
Methods: In this prospective study, flexible bronchoscopy was used for cryorecanalization of 72 patients with high grade stenoses of the respiratory tract from exophytic tumors. Tumor tissue was frozen on the tip of the probe and subsequently removed from the surrounding respiratory tract tissue by retraction of the probe. Procedures were carried out on sedated, spontaneously breathing, intubated patients.
Results: 58 of 72 patients were successfully or partially successfully treated. Tumor bleeding occurred in 7 cases, but was stopped endoscopically in all cases, not requiring rigid bronchoscopy.
Conclusion: Cryorecanalization with the newly developed cryoprobe permits effective and safe therapy on endobronchial stenoses of the respiratory tract. Extended numbers of patients treated showed promising results, which could make cryorecanalization to an alternative recanalization procedure. However the superiority in terms of safety and efficacy still remains to be shown.

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Citations should be made in the following way:
A. J. Babiak, C. Schumann, J. Hetzel, M. Hetzel (Ulm, Germany). Cryorecanalization - a new method to overcome airway obstruction from exophytic tumors. Eur Respir J 2004; 24: Suppl. 48, 4290

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