Nrf2 is closely related to enhance bleomycin induced airway inflammatory responses caused by diesel exhaust particles in mice

Y.J. Li, T. Shimizu, Y. Hirata, H. Inagaki, Y. Shinkai, K. Takeda, A. Azuma, H. Takizawa, Y. Masayuki, T. Kawada, S. Kudoh (Tokyo, Noda, Mitaka, Sendai, Kiyose, Japan)

Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Session: Fibrogenesis between epithelial injury and fibroblast proliferation
Session type: Thematic Poster Session
Number: 3748
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Y.J. Li, T. Shimizu, Y. Hirata, H. Inagaki, Y. Shinkai, K. Takeda, A. Azuma, H. Takizawa, Y. Masayuki, T. Kawada, S. Kudoh (Tokyo, Noda, Mitaka, Sendai, Kiyose, Japan). Nrf2 is closely related to enhance bleomycin induced airway inflammatory responses caused by diesel exhaust particles in mice. Eur Respir J 2012; 40: Suppl. 56, 3748

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
PP123 – Dimethyl fumarate attenuates lung inflammation and oxidative stress induced by chronic exposure to diesel exhaust particles in mice
Source: ERS Lung Science Conference 2021
Year: 2021

Diesel exhaust inhalation causes elevated oxidative burst in airway macrophages and neutrophils that is mitigated by anti-oxidant supplementation
Source: Annual Congress 2010 - Causal factors and mechanisms of outdoor air pollution and nanoparticulates
Year: 2010


Airway cells exposed to wildfire smoke extract exhibit dysregulation of autophagy and changes characteristic of inflammatory airway disease.
Source: International Congress 2017 – Current molecular and genetic understanding of lung diseases
Year: 2017

Chronic exposure of diesel exhaust particles causes alveolar enlargement in mice
Source: Annual Congress 2011 - Environmental exposure and disease mechanisms
Year: 2011


Junctional modulation by lipopolysaccharide on epithelial damage caused by diesel exhaust particles
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018

Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung
Source: Eur Respir J 2006; 28: 275-285
Year: 2006



Low dose diesel exhaust particle exposure exacerbates allergic asthma in young mice
Source: Annual Congress 2012 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2012


Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel
Source: Eur Respir J 2004; 23: 82-86
Year: 2004



Lung inflammatory response after subacute exposure to diesel exhaust particles from são paulo in mice
Source: Annual Congress 2009 - Occupational exposures and disease II
Year: 2009


Effects of swimming on lung inflammation and oxidative stress in diesel exposed mice
Source: Annual Congress 2012 - Indoor and outdoor air pollution
Year: 2012

Diesel exhaust enhances airway responsiveness in asthmatic subjects
Source: Eur Respir J 2001; 17: 909-915
Year: 2001



Increase in markers of airway inflammation after ozone exposure can be observed also in subjects who do not functionally respond to ozone
Source: Eur Respir J 2007; 30: Suppl. 51, 750s
Year: 2007

The cellular impacts of diesel exhaust particles: beyond inflammation and death
Source: Eur Respir J 2006; 27: 667-668
Year: 2006


Inhalation of extrinsic aerosol rIL-10 suppressed eosinophilia in airway of sensitized mice
Source: Eur Respir J 2006; 28: Suppl. 50, 225s
Year: 2006

The role of glutaredoxin-1 in pulmonary inflammation induced by diesel exhaust particles
Source: Annual Congress 2013 –Murine models of lung immunology
Year: 2013


Protective effect of curcumin on pulmonary and cardiovascular effects induced by repeated exposure to diesel exhaust particles
Source: Annual Congress 2012 - Indoor and outdoor air pollution
Year: 2012

Protective effects of nootkatone against particles-induced lung injury caused by diesel exhaust is mediated via the NF-?B pathway
Source: International Congress 2018 – Occupational and environmental lung diseases: inhaled air quality and health effects
Year: 2018

Diesel exhaust exposure enhances the ozone-induced airway inflammation in healthy humans
Source: Eur Respir J 2008; 31: 1234-1240
Year: 2008



N-acetylcysteine prevents pulmonary decrement and neutrophils recruitment in the airways but does not reduce the products of oxidative stress due to ozone exposure in asthmatics
Source: Annual Congress 2008 - Occupational asthma - agents and management
Year: 2008

Intranasal dust exposure decreases Th2 driven allergic inflammation and increases the Th17 response in mice
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009