Relationship between six-minute walk distance and chronic obstructive pulmonary disease assessment test
S. Dürr, S. Zogg, S. Maier, E. H. Steveling, D. Miedinger, J. D. Leuppi (Basel, Zurich, Switzerland)
Source: Annual Congress 2012 - Various issues in clinical physiology
Session: Various issues in clinical physiology
Session type: Thematic Poster Session
Number: 3800
Disease area: Airway diseases
Abstract Background: Many patients with chronic obstructive pulmonary disease (COPD) are affected by the impairment in the ability to perform daily physical activities due to exercise intolerance, which can lead to a poor health-related quality of life. Aims and objectives: Our aim was to investigate the association of the six-minute walk distance (6MWD) and the COPD assessment test (CAT). We hypothesized that physical capacity has a more relevant association with quality of life than lung function. Methods: This cross-sectional study was conducted in 2011 at the University Hospital of Basel, Switzerland. Patients with COPD stages I to IV were investigated. Functional exercise capacity was measured by the six-minute walk test according to the guidelines of the American Thoracic Society. Spirometry was performed according to current guidelines. Health status was assessed by the CAT. A forced entry multiple regression analysis was calculated. The regression included 6MWD, forced expiratory volume in one second in % of predicted (FEV1 %predicted), age and Body-Mass-Index (BMI). The dependent variable was the CAT-score. Results: Complete data were available for 73 individuals (age 67.0 ±9.8yrs, 58.9% male, FEV1 %predicted 69.7 ±23.7%, 6MWD 434.5 ±99.1m, CAT-score 12.5 ±6.8, BMI 25.7 ±5.5). Age and 6MWD significantly contributed to the model (β= -0.49 respectively β= -0.46, p<0.01). BMI and FEV1 %predicted did not significantly influence the CAT-score (β= -0.14 respectively β= -0.13). Conclusion: The association of the 6MWD and the CAT-score indicates that higher physical fitness level is related to improved health status and thus decreased impact of COPD on an individual‘s life.
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S. Dürr, S. Zogg, S. Maier, E. H. Steveling, D. Miedinger, J. D. Leuppi (Basel, Zurich, Switzerland). Relationship between six-minute walk distance and chronic obstructive pulmonary disease assessment test. Eur Respir J 2012; 40: Suppl. 56, 3800
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