ERK MAP kinase is upregulated in pulmonary emphysema and mediates MMP-1 induction by cigarette smoke Source: Eur Respir J 2004; 24: Suppl. 48, 437s Year: 2004
Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
Cigarette smoke exposure disrupts VEGF signalling through the kinase insert-domain receptor (KDR) in rat lungs Source: Eur Respir J 2004; 24: Suppl. 48, 30s Year: 2004
Cigarette smoke decreases E-Cadherin expression downregulating FoxO3 in lung epithelial cells Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD Year: 2019
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
Exposure to LPS induces the upregulation of p38 MAPK in human bronchial epithelium in vivo Source: Eur Respir J 2003; 22: Suppl. 45, 459s Year: 2003
Cigarette smoke upregulating the expression of miR 21 increases IL-8 in airway epithelial cells Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases Year: 2018
Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 454s Year: 2004
Tobacco smoke induces muc5AC expression in normal bronchial epithelial cells trough activation of the NADPH system in a mechanism involving EGF-R activation Source: Annual Congress 2009 - Translational models of lung disease Year: 2009
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Inhibitory effects of the IL-6 receptor superantagonist SANT7 on MAP kinase phosphorylation and cell proliferation induced by IL-6 and TGF-beta1 in human lung fibroblasts Source: Annual Congress 2008 - Clinical aspects of interstitial lung disease Year: 2008
YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Overexpression of CBP augments cigarette smoke-induced pro-inflammatory cytokine release in macrophages Source: Eur Respir J 2005; 26: Suppl. 49, 105s Year: 2005
Cigarette smoke suppresses mast cell maturation and cytokine release independent of TLR4 signaling Source: Annual Congress 2012 - Basic and translational studies in COPD Year: 2012
Cigarette smoke induce Epithelial-Derived Inflammation through activating autophagy via RAGE signaling in bronchial epithelial cells. Source: International Congress 2019 – Effects of environmental exposures in lung pathology and the underlying mechanisms Year: 2019
Effect of smoking on MAP kinase-induced modulation of IL-8 in human alveolar macrophages Source: Eur Respir J 2004; 23: 805-812 Year: 2004
Cigarette smoke enhances beta-defensin 2 expression in rat airways via nuclear factor-kappa-B activation Source: Eur Respir J 2010; 36: 638-645 Year: 2010