Differential response to stretch in different lung cells is related to differences in pi3k signalling Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury Year: 2009
Autocrine secretion of bradykinin prevents alveolar type II cells from mechanical stretch-induced apoptosis by activation – role of PI3K and Akt Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury Year: 2008
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
The growth factors HGF and KGF prevent mechanical stretch-induced apoptosis of alveolar Type II cells by restoration of mechanical stretch-induced decreased phosphatidylinositol 3-OH kinase (PI3K) activity Source: Eur Respir J 2006; 28: Suppl. 50, 568s Year: 2006
N-acetylcysteine reduces chemokine release via inhibition of p38 MAPK in human airway smooth muscle cells Source: Eur Respir J 2003; 22: 43-49 Year: 2003
p38 MAP kinase mediates apoptosis related to ventilator associated lung injury Source: Annual Congress 2008 - Pulmonary vascular biology Year: 2008
Bile acid receptor accelerates to the lung cancer process induced by lung fibroblast-tumor cells interaction, with high activation of phosphorylated STAT3 and alteration of cytokine secretion Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench Year: 2017
Effect of activated protein C on the thrombin signalling pathway in alveolar epithelial cells Source: Annual Congress 2009 - Acute lung injury: biological mechanisms Year: 2009
Potential role of filamin and p38 MAPK in the regulation of human alveolar epithelial cell permeability Source: Eur Respir J 2002; 20: Suppl. 38, 96s Year: 2002
Mitogen activated protein kinase activated protein kinase 2 regulates actin stress fiber formation in ventilator associated lung injury Source: Annual Congress 2008 - Pulmonary vascular biology Year: 2008
Decreased PTEN amplifies PI3K signaling and enhances pro-inflammatory cytokine release in COPD Source: International Congress 2016 – Studies in airway cell biology Year: 2016
A differential role for ceramide kinase in antigen/FcεRI mediated mast cell activation and function Source: Eur Respir J 2006; 28: Suppl. 50, 231s Year: 2006
Corticosteroids reduce pro-inflammatory cytokine expression in airway smooth muscle cells via upregulation of MAPK phosphatase-1 and inhibition of p38 MAPK signalling Source: Eur Respir J 2005; 26: Suppl. 49, 713s Year: 2005
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007
PI3K and notch signal pathways coordinately regulate the activation and proliferation of T lymphocytes in asthma Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation Year: 2013
Activation of ERK and AKT kinase by ventilation in an animal model of prolonged stretch due to exogenous surfactant Source: Eur Respir J 2003; 22: Suppl. 45, 210s Year: 2003
TNF-α-induced CD38 expression in human airway smooth muscle cells: role of PI3K/Akt pathway Source: Annual Congress 2008 - Airway cell biology and immunology Year: 2008
CAM-kinase II inhibition and protein kinase C activation combine synergistically to initiate ciliary beat frequency despite cellular hypothermia Source: Eur Respir J 2002; 20: Suppl. 38, 88s Year: 2002
YKL-40 induces IL-8 expression from bronchial epithelium via MAPK (JNK, ERK1/2) and NF-κB pathways, causing bronchial smooth muscle proliferation and migration Source: Annual Congress 2012 - Asthma: mechanisms of airway inflammation Year: 2012
Exposure to LPS induces the upregulation of p38 MAPK in human bronchial epithelium in vivo Source: Eur Respir J 2003; 22: Suppl. 45, 459s Year: 2003