Source: Annual Congress 2012 - Various issues in clinical physiology
Disease area: Airway diseases

Abstract

Aim: Investigate the RM status.
Material, Methods: We obtained the indices: homogenity (H), structural density (SD), echogenicity (E) and dispersion (D) of the internal oblique abdominal muscle (intOAM) by ultrasonic scanner. We carried out histological research of intOAM. Research was made in 20 COPD pts: 1st group (10 – 1st stage); 2nd group (10 – 2nd stage). Control - 12 healthy subjects.
Results: There have been areas of myolysis, cell proliferation of perimiysium, ²ingrowth² of fatty tissue between myofibrils (MF). There is interstitial sclerosis, sections "contractions" of MF. Among the relatively preserved MF was found deep dystrophic one with protein granules of different sizes in the appearance of the sarcoplasm. The H in pts of the 1st and 2nd groups was 20.8 and 19.3 respectively (p< 0.05). The E also was different in pts of the 1st and 2nd groups (3.7 and 4.8). The D was increased in the 2nd group 18.6 vs. the 1st group 17.5. The SD had the tendency to decrease. Increasing of COPD severity was associated with significant enhancing of "contractions" (r=0.72), destruction of MF (r=0.69) and proliferation of fibroblasts (r=0.52). We detected the presence of negative correlations between H, SD and sclerosis (r=-0.39 and r=-0.51 respectively). Meanwhile the E was higher in these pts and correlated directly (r=0.48; p<0.05). The D was increased in the presence of fragmentation of MF (r=0.52). The E correlated in the 2nd group with fat mass (r=0.62). This may indicate the accumulation of intramuscular fat in the second stage.
Conclusion: The proposed echodensitometric parameters reflect the degenerative processes occurring in the RM.

Rating:

Share or cite this content

Citations should be made in the following way:
A. Lemeschewskij, M. Nedzvedz, A. Pochtavcev, A. Makarevich, S. Lemiasheuskaya (Minsk, Belarus). The estimation of respiratory muscles (RM) status by echodensitometry in men with chronic obstructive pulmonary disease (COPD). Eur Respir J 2012; 40: Suppl. 56, 3803

Member's Comments

No comment yet.

Related content which might interest you: Changes of active expiration respiratory muscle (RM) in men with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2011 - Respiratory and skeletal muscle assessment in health and disease Year: 2011 The relationship between echodensitometric parameters of respiratory muscles (RM) and indices of body composition (IBC) in men with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2011 - Morphological and functional imaging in obstructive airway disease Year: 2011 Benefits of pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) having the same dyspnoea severity Source: International Congress 2018 – What’s hot in rehabilitation in COPD and interstitial lung disease (ILD)? Year: 2018 Influence of tobacco smoking on respiratory muscles function in patients with chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2006; 28: Suppl. 50, 247s Year: 2006 The indices of body composition (IBC) in chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2011 - COPD diagnosis Year: 2011 Measurement of improved activities after pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2001; 18: Suppl. 33, 223s Year: 2001 The state of patients with chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2007; 30: Suppl. 51, 547s Year: 2007 Pulmonary rehabilitation (PR) outcomes in chronic obstructive pulmonary disease (COPD) compared with interstitial lung disease (ILD) Source: Annual Congress 2011 - Pulmonary rehabilitation: looking at alternative approaches and alternative populations beyond COPD Year: 2011 Differential therapy of acute respiratory failure (ARF) in chronic obstructive pulmonary disease (COPD) patients with predominance of emphysema (PE) and predominance of bronchitis (PB) Source: Eur Respir J 2006; 28: Suppl. 50, 395s Year: 2006 Effect of hospitalization on exercise capacity in patients with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2012 - Methodology in epidemiologic research Year: 2012 The effect of dipyrone on respiratory function in chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2004; 24: Suppl. 48, 290s Year: 2004 The dynamic lung volume analysis in chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2005; 26: Suppl. 49, 212s Year: 2005 The metabolic syndrome (MetS) in patients with chronic obstructive pulmonary disease (COPD) and its association with airway obstruction Source: Annual Congress 2012 - COPD is not a pulmonary disease alone Year: 2012 Effects of a respiratory rehabilitation program over pulmonary hypertension (PH) and other right ventricular function measurements in a chronic obstructive pulmonary disease (COPD) population Source: Virtual Congress 2020 – The multiple facets of pulmonary rehabilitation and chronic respiratory care Year: 2020 The estimation of respiratory muscles (RM) status by echodensitometry in male patients with acute exacerbation of COPD (AECOPD) Source: Annual Congress 2010 - Interaction between respiratory and peripheral muscles Year: 2010 Reproducibility of quadriceps strength measurements in patients with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2010 - Outcomes in chronic lung disease: assessing the value of interventions – physical activity, strength and exercise Year: 2010 Does tolerance of neuro-muscular electrical stimulation (NMES) relate to gender in patients with an acute exacerbation (AE) of chronic obstructive pulmonary disease (COPD)? Source: Annual Congress 2012 - Physiotherapy and rehabilitative interventions applied to different populations with respiratory impairment Year: 2012 How to measure nutritional status before physical training in patients with chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2004; 24: Suppl. 48, 292s Year: 2004 The influence of co-morbidity on the outcome of non-invasive ventilatory support in patients with acute respiratory failure (ARF) in chronic obstructive pulmonary disease (COPD) Source: Eur Respir J 2002; 20: Suppl. 38, 277s Year: 2002 Distribution of leg muscle weakness in chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2008 - Assessing profiles of rehabilitation candidates Year: 2008