Ghrelin ameliorates bleomycin-induced acute lung injury by protecting alveolar epithelial cells and suppressing lung inflammation

S. Yanagi, Y. Imazu, K. Miyoshi, H. Tsubouchi, N. Matsumoto, M. Nakazato (Miyazaki, Japan)

Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Session: Fibrogenesis between epithelial injury and fibroblast proliferation
Session type: Thematic Poster Session
Number: 3750
Disease area: Interstitial lung diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Yanagi, Y. Imazu, K. Miyoshi, H. Tsubouchi, N. Matsumoto, M. Nakazato (Miyazaki, Japan). Ghrelin ameliorates bleomycin-induced acute lung injury by protecting alveolar epithelial cells and suppressing lung inflammation. Eur Respir J 2012; 40: Suppl. 56, 3750

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Effects of autophagy on LPS-induced lung inflammation and acute lung injury (ALI) in vitro and in vivo
Source: International Congress 2018 – Role of microbial exposure and inflammation in lung injury
Year: 2018

Chronic intermittent hypoxia exacerbates lung fibrosis in bleomycin-induced lung injury mouse model
Source: International Congress 2018 – Sleep-disordered breathing: cardiovascular consequences, epidemiology, phenotypes and comorbidities
Year: 2018



Dexamethasone reduces lung inflammation induced by alveolar stretch in mice
Source: Annual Congress 2011 - Anti-inflammatory strategies in acute lung injury
Year: 2011

Role of alveolar macrophages in acute lung injury model
Source: International Congress 2017 – Anti-inflammatory and pro-repair mediators in acute lung injury
Year: 2017

IL-9 protects against bleomycin-induced lethal lung injury through a prostaglandin-dependent mechanism
Source: Eur Respir J 2004; 24: Suppl. 48, 105s
Year: 2004

Preferential activation of alveolar macrophages versus epithelial cells during initiation of ventilator-induced lung injury in mice
Source: Annual Congress 2011 - Lung cell injury and repair
Year: 2011


Reduction of lung injury and fibrosis by human embrionic stem cells in a mouse model of silica-induced lung fibrosis
Source: Annual Congress 2011 - Experimental models and research in diffuse parenchymal lung diseases
Year: 2011

Phenotipic diferences between alveolar and interstitial macrophages in acute lung injury induced by pancreatitis
Source: Annual Congress 2010 - Determinants of acute lung injury and fibrosis
Year: 2010

Rikkunshito ameliorates bleomycin-induced lung injury in mice
Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Year: 2012

Apoptotic cell instillation after bleomycin attenuates lung injury through hepatocyte growth factor induction
Source: Eur Respir J 2012; 40: 424-435
Year: 2012



The role of osteopontin in the pulmonary fibrosis caused by acute lung injury induced by lipopolysaccharide in rats
Source: Annual Congress 2011 - Acute respiratory failure
Year: 2011

PD98059 attenuates the development of bleomycin-induced lung injury and fibrosis
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Kallistatin protects against LPS-induced mouse lung injury
Source: Annual Congress 2012 - The many roads to lung injury
Year: 2012


The influence of dexamethasone on the proliferation and apoptosis of pulmonary inflammatory cells in bleomycin-induced pulmonary fibrosis in rats
Source: Eur Respir J 2002; 20: Suppl. 38, 487s
Year: 2002

The role of leptin in pulmonary neutrophilia during murine acute lung injury
Source: Annual Congress 2011 - Lung cell injury and repair
Year: 2011

Pioglitazone attenuates endotoxin-induced acute lung injury by reducing neutrophil recruitment
Source: Eur Respir J 2012; 40: 416-423
Year: 2012



Ghrelin protects against bleomycin-induced pulmonary fibrosis in mice
Source: International Congress 2017 – Lung fibrosis: basic science
Year: 2017


Curcumin inhibits COPD-like airway inflammation and lung cancer promotion in mice
Source: Annual Congress 2009 - COPD and asthma - from the cell to the clinic
Year: 2009


PKA- and Epac/Rap-dependent mechanisms of lung endothelial barrier protection in acute lung injury
Source: Annual Congress 2009 - Highlighting the epithelial cell in lung disease: from COPD to cancer to acute lung injury
Year: 2009


The role of pendrin in acute lung injury caused by ventilator-induced lung injury
Source: Virtual Congress 2020 – Mechanistic insight into lung injury and repair
Year: 2020