Randomised controlled trial for emphysema with a selective agonist of the ?-type retinoic acid receptor

Stolk Jan, Stockley Robert A., Stoel Berend C., Cooper Brendan G., Piitulainen Eeva, Seersholm Niels, Chapman Kenneth R., Burdon Jonathan G.W., Decramer Marc, Abboud Raja T., Mannes Gregorius P.M., Wouters Emiel F., Garrett Jeffrey E., Barros-Tizon Juan C., Russi Erich W., Lomas David A., MacNee William A., Rames Alexis

Source: Eur Respir J 2012; 40: 306-312
Journal Issue: August
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Stolk Jan, Stockley Robert A., Stoel Berend C., Cooper Brendan G., Piitulainen Eeva, Seersholm Niels, Chapman Kenneth R., Burdon Jonathan G.W., Decramer Marc, Abboud Raja T., Mannes Gregorius P.M., Wouters Emiel F., Garrett Jeffrey E., Barros-Tizon Juan C., Russi Erich W., Lomas David A., MacNee William A., Rames Alexis. Randomised controlled trial for emphysema with a selective agonist of the ?-type retinoic acid receptor. Eur Respir J 2012; 40: 306-312

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Formoterol in patients with chronic obstructive pulmonary disease: a randomized, controlled, 3-month trial.
Source: Eur Respir J 2002; 20: 245
Year: 2002


A randomised, controlled trial of bosentan in severe COPD
Source: Eur Respir J 2008; 32: 619-628
Year: 2008



Inhaled rhGM-CSF (molgramostim) in the first randomised, double-blind, placebo-controlled, international trial in patients with autoimmune alveolar proteinosis (aPAP)
Source: International Congress 2016 – Orphan diseases I
Year: 2016

Short term glucocorticoid therapy in acute exacerbations of chronic obstructive pulmonary disease: "REDUCE*", a non-inferiority multicenter trial. (*Reduction in the Use of Corticosteroids in Exacerbated COPD; ISRCTN19646069)
Source: Annual Congress 2012 - Acute exacerbation in COPD
Year: 2012

The effects of oral clarithromycin on airway inflammation in moderate to severe chronic obstructive pulmonary disease (COPD) - a double blind randomised controlled trial
Source: Eur Respir J 2001; 18: Suppl. 33, 338s
Year: 2001

RCT Abstract - Cyclophosphamide added to glucocorticoids in acute exacerbation of idiopathic pulmonary fibrosis (EXAFIP): a randomized, double-blind, placebo-controlled, phase 3 trial
Source: Virtual Congress 2021 – ALERT: Asthma in adult, in children and ILDs
Year: 2021



Late Breaking Abstract - First-time assessment of efficacy of candidate vaccine to prevent acute exacerbations of chronic obstructive pulmonary disease (AECOPD): multicentre, randomised, controlled, observer-blind phase 2b trial
Source: Virtual Congress 2021 – ALERT: COPD
Year: 2021



Effects of combined therapy with nebulized b2-agonist and anticholinergic in severe exacerbation of chronic obstructive pulmonary disease. Randomized controlled trial
Source: Eur Respir J 2007; 30: Suppl. 51, 611s
Year: 2007

Design and rationale of two phase 3 randomised controlled trials (COUGH-1 and COUGH-2) of gefapixant, a P2X3 receptor antagonist, in refractory or unexplained chronic cough
Source: ERJ Open Res, 6 (4) 00284-2020; 10.1183/23120541.00284-2020
Year: 2020



Angiotensin II blockers in obstructive pulmonary disease: a randomised controlled trial
Source: Eur Respir J 2006; 27: 972-979
Year: 2006



Efficacy of moxifloxacin for treatment of bronchial colonisation in COPD patients: a randomised, double-blind, placebo-controlled study
Source: Annual Congress 2007 - Treatment and care of COPD
Year: 2007



A randomised, placebo-controlled study of omipalisib (PI3K/mTOR) in idiopathic pulmonary fibrosis
Source: Eur Respir J, 53 (3) 1801992; 10.1183/13993003.01992-2018
Year: 2019



Cilomilast reduces CD8+ T-lymphocytes and macrophages in patients with chronic obstructive pulmonary disease (COPD): a double-blind placebo-controlled, parallel-group quantitative study of bronchial biopsies
Source: Eur Respir J 2001; 18: Suppl. 33, 338s
Year: 2001

Formoterol in patients with chronic obstructive pulmonary disease: a randomized, controlled, 3-month trial
Source: Eur Respir J 2002; 19: 936-943
Year: 2002



Late Breaking Abstract - Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease - COPD-ST2OP: a phase IIa, placebo-controlled trial
Source: Virtual Congress 2021 – ALERT: COPD
Year: 2021



The utility of tiotropium among patients with chronic obstructive pulmonary disease (COPD): An updated meta-analysis of randomized controlled trials
Source: Annual Congress 2013 –Quality of diagnosis and assessment in primary care
Year: 2013


Design of phase 2b randomised controlled trial of S-600918, P2X3 receptor antagonist for refractory chronic cough
Source: Virtual Congress 2020 – Asthma and cough: clinical trials and pharmacological insights
Year: 2020


Effects of Roflumilast on subclinical atherosclerosis in COPD - a randomized controlled trial
Source: International Congress 2017 – Extrapulmonary comorbidities in COPD
Year: 2017

Preliminary results of a prospective, multicentric randomized study comparing Interferon Gamma-1b (IFN-γ) and colchicine in the treatment of idiopathic pulmonary fibrosis (IPF)
Source: Annual Congress 2003 - Interstitial lung diseases
Year: 2003


Recent clinical trials in idiopathic pulmonary fibrosis and the BUILD-1 study
Source: Eur Respir Rev 2008; 17: 116-122
Year: 2008