Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD

Pera T., Zuidhof A., Valadas J., Smit M., Schoemaker R.G., Gosens R., Maarsingh H., Zaagsma J., Meurs H.

Source: Eur Respir J 2011; 38: 789-796
Journal Issue: October
Disease area: Airway diseases

Congress or journal article abstractFull text journal articlePDF journal article, handout or slides

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Pera T., Zuidhof A., Valadas J., Smit M., Schoemaker R.G., Gosens R., Maarsingh H., Zaagsma J., Meurs H.. Tiotropium inhibits pulmonary inflammation and remodelling in a guinea pig model of COPD. Eur Respir J 2011; 38: 789-796

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Allergic lung inflammation induces pulmonary vascular hyperresponsiveness
Source: Eur Respir J 2006; 28: 370-377
Year: 2006



Effects of physical stress on lung mechanics, distal airway eosinophilic and lymphocytic inflammation, IL-13 expression and extracellular matrix remodeling in guinea pigs with chronic pulmonary inflammation
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009


Allergen-induced airway remodelling
Source: Eur Respir J 2007; 29: 1020-1032
Year: 2007



Increased arginase activity contributes to airway remodelling in chronic allergic asthma
Source: Eur Respir J 2011; 38: 318-328
Year: 2011



Mast cells in COPD airways: relationship to bronchodilator responsiveness and angiogenesis
Source: Eur Respir J 2012; 39: 1361-1367
Year: 2012



Neurokinins contribute to vascular remodelling in a model of chronic pulmonary allergic inflammation
Source: Eur Respir J 2006; 28: Suppl. 50, 760s
Year: 2006

Glucagon inhibits airway hyperreactivity and lung inflammation in a murine model of acute lung injury
Source: International Congress 2015 – Therapeutic approaches in inflammatory lung disease
Year: 2015

Osteopontin exacerbates airway hyperresponsiveness and lung remodeling in chronic asthma
Source: Annual Congress 2008 - Basic science in asthma and COPD
Year: 2008

The novel compound Sul-121 inhibits inflammation in experimental models of chronic obstructive pulmonary disease
Source: International Congress 2016 – New signalling pathways in COPD
Year: 2016

Cigarette smoke-induced pulmonary inflammation, but not airway wall remodeling, is attenuated in CCR5 deficient mice
Source: Annual Congress 2007 - The best of airway epithelial cells
Year: 2007



Basic mechanisms of development of airway structural changes in asthma
Source: Eur Respir J 2007; 29: 379-389
Year: 2007



Mechanisms of bronchial hyperresponsiveness in a clinical setting – putative role of smooth muscle
Source: Annual Congress 2005 - Role of the bronchial smooth muscle in regulating airway disease
Year: 2005

Tools used to measure airway remodelling in research
Source: Eur Respir J 2007; 29: 596-604
Year: 2007



Involvement of FHL1 in vascular remodelling
Source: Annual Congress 2006 - Lung vascular and parenchymal remodeling
Year: 2006


Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats
Source: Eur Respir J 2011; 37: 1104-1118
Year: 2011



Inhaled doxycycline reduces allergen-induced airway inflammation, hyperresponsiveness and remodelling in mice
Source: Annual Congress 2005 - Inflammation and remodelling in allergy and asthma
Year: 2005


Update on the roles of distal airways in COPD
Source: Eur Respir Rev 2011; 20: 7-22
Year: 2011



The role of small airways in obstructive airway diseases
Source: Eur Respir Rev 2011; 20: 23-33
Year: 2011



Capsaicin-sensitive nerves inactivation reduces lung parenchyma remodeling in guinea pigs with chronic allergic pulmonary inflammation
Source: Annual Congress 2008 - Animal models of pulmonary fibrosis: mechanisms and therapies
Year: 2008

Mast cells promote lung vascular remodelling in pulmonary hypertension
Source: Eur Respir J 2011; 37: 1400-1410
Year: 2011