Source: Annual Congress 2004 - Lung function technology: beyond the basic test
Disease area: Airway diseases

Abstract

Background Expiratory flow limitation is a common symptom of the group of diseases known as chronic obstructive pulmonary disease (COPD). The degree of flow limitation has been traditionally assessed using spirometry techniques. This technique for assessing flow limitation has been shown to have potential inaccuracies for a number of reasons so the negative expiratory pressure (NEP) method has been developed as a new method for assessing the degree of flow limitation within COPD patients. The present study was designed to assess the repeatability of the NEP method of flow limitation in a COPD population.
Methods: The repeatability of the NEP method was assessed in 54 COPD patients previously diagnosed using GOLD guidelines. Each subject was tested for flow limitation 5 times using the NEP method in the seated position. ( Medisoft, Dinant, Belgium). To assess the repeatability of NEP, a coefficient of variation, (standard deviation /Ö2)/ mean) , was calculated from the % flow limitation and the ΔFlow measurements for each COPD patient.
Results: The results showed that the coefficient of variation for % Flow limitation and for ΔFlow was 7.40% and 8.62% respectively there was a tendency for the repeatibility to improve as the %Flow limitation increased .
Conclusion: The within-occasion repeatability of the NEP technique is comparable to other measures used within the pulmonary function laboratory and as such could be a useful addition to the tools already at play in the diagnosis of Respiratory Disease.

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Citations should be made in the following way:
R. J. Hawksworth, S. J. Lane (Dublin, Ireland). The repeatability of the negative expired method (NEP) in assessing flow limitation in COPD patients. Eur Respir J 2004; 24: Suppl. 48, 2491

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