Source: Annual Congress 2004 - Lung function technology: beyond the basic test
Disease area: Airway diseases

Abstract

Introduction
One of the goals of a rehabilitation program for patients with Chronic Obstructive Pulmonary Disease (COPD) is to increase muscle mass. Mostly this muscle mass is estimated by measuring bio-impedance of the whole body, however little is known about the intra-subject variability.
Aim
To assess the intra-subject variability of the bio-impedance measurement in healthy subjects and COPD patients.
Subjects
18 Healthy subjects (4 male/14 female, mean age 38 yrs, mean BMI 24 kg/m²) and 18 COPD patients (12 male/6 female, mean age 64 yrs, mean BMI 28 kg/m² ).
Method
Bio-impedance measurements were performed twice, with an exact 24 hour interval, using the Bodystat® 1500 (Bodystat, England). Oral intake was not allowed in the 2 hours preceding the measurement.
Results

Mean (SD) difference in healthy and COPD subjects: -11 (28) Ohm (p = 0.24), and 14 (27) Ohm (p = 0.06) respectively.
Conclusion
No significant differences between two measurements within 24 hours were found, neither in healthy subjects, nor in COPD-patients. However, intra-subject variability was high in both groups.

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Citations should be made in the following way:
M. T. van Hoogdalem, M. Leever-Harkema, E. Eringa, A. Dijkstra, J. B. Wempe, N. H. T. Ten Hacken (Groningen, The Netherlands). Intra-subject variability of bio-impedance measurements in healthy subjects and COPD-patients. Eur Respir J 2004; 24: Suppl. 48, 2482

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