Proteinase inhibition regulates the anti-tumor activity of PAI-1 towards lung and prostate cancer cells

A. Rozy, M. Kedzior, J. Chorostowska-Wynimko, P. Jagus, A. Szpechcinski, E. Skrzypczak-Jankun, J. Jankun (Warsaw, Poland; Toledo, United States Of America)

Source: Annual Congress 2011 - Lung cancer: molecular pathology and functional genomics
Session: Lung cancer: molecular pathology and functional genomics
Session type: Poster Discussion
Number: 1962
Disease area: Thoracic oncology

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
A. Rozy, M. Kedzior, J. Chorostowska-Wynimko, P. Jagus, A. Szpechcinski, E. Skrzypczak-Jankun, J. Jankun (Warsaw, Poland; Toledo, United States Of America). Proteinase inhibition regulates the anti-tumor activity of PAI-1 towards lung and prostate cancer cells. Eur Respir J 2011; 38: Suppl. 55, 1962

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Diverse effects of PAI-1 proteins on lung and prostate cancer cell invasion
Source: Annual Congress 2011 - Lung development and neoplasia
Year: 2011


Adipocyte-derived exosomes promote lung cancer metastasis byincreasing MMP9 activity via transferring MMP3 to lung cancer cells
Source: International Congress 2017 – Basic research in lung cancer: a scientific potpourri from genetic alterations to immune cells
Year: 2017

Heparins inhibit lung cancer cells proliferation in vitro
Source: Annual Congress 2008 - Biology and prognosis in thoracic oncology
Year: 2008


The human endogenous antibiotic LL-37 promotes growth of lung cancer cells
Source: Eur Respir J 2006; 28: Suppl. 50, 153s
Year: 2006

Caspase recruitment domain containing protein 9 suppresses non-small cell lung cancer proliferation and invasion via inhibiting MAPK/p38 pathway
Source: Virtual Congress 2020 – Molecular alterations and immunology in lung cancer
Year: 2020

Over-expression of aquaporin-5 increases migration and metastatic potential of lung cancer cells
Source: Annual Congress 2009 - Hot topics in molecular pathology and functional genomics of lung cancer
Year: 2009


HIF-1α modulation by topoisomerase inhibitors in A549, a non-small cell lung cancer cell line
Source: Annual Congress 2007 - Biology in thoracic oncology
Year: 2007


Proapoptotic and anti-proliferative effect of the stable plasminogen activator inhibitor type 1 (PAI-1) mutant on the lung cancer and endothelial cells
Source: Annual Congress 2009 - What is new in molecular pathology and functional genomics of neoplastic and non-neoplastic lung disease?
Year: 2009


GSK-3 inhibition suppresses lung cancer cell survival, metastasis and proliferation through down-regulation the phosphorylation sites of CAP1
Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench
Year: 2017

MicroRNA-101 inhibits lung cancer growth and invasion through regulation of EZH2
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Functional expressions of EGFP/LKB1 and its kinase domain induced apoptosis and enhanced chemosensitivity in lung cancer cell lines
Source: Eur Respir J 2004; 24: Suppl. 48, 5s
Year: 2004

D104N poluymorphism in endostatin, an angiogenesis inhibitor, in lung cancer susceptibility
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Specific plasmids encoding shRNA molecules directed against growth factor receptors in cell proliferation inhibition and induction phenotype changes relevant to enhancement of anti-tumor immunity. Model of human non-small (NSCLC) and small (SCLC) cell lung cancer lines
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Interleukin-17 enhances the net angiogenic potential and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis
Source: Eur Respir J 2004; 24: Suppl. 48, 79s
Year: 2004

Salinomycin suppresses TGF-ß1-induced EMT by down-regulating MMP-2,9 via AMPK-SIRT1 pathway in a non-small cell lung cancer
Source: International Congress 2017 – Basic research in lung cancer: a scientific potpourri from genetic alterations to immune cells
Year: 2017

Deguelin enhances chemosensitivity of non-small cell lung cancer cells
Source: Eur Respir J 2006; 28: Suppl. 50, 336s
Year: 2006

Tissue inhibitor of metalloproteinase 3 inhibits growth of lung cancer tumours in nude mice
Source: Eur Respir J 2004; 24: Suppl. 48, 704s
Year: 2004

Elevated endogenous thrombin potential in patients with lung cancer
Source: Eur Respir J 2003; 22: Suppl. 45, 199s
Year: 2003

IRP2 as a potential modulator of cell proliferation, apoptosis and prognosis in nonsmall cell lung cancer
Source: Eur Respir J , 49 (4)  1600711; DOI: 10.1183/13993003.00711-2016
Year: 2017



Toll-like receptor 3 is up-regulated and enhances anti-proliferative function in human non-small cell lung cancer
Source: Annual Congress 2008 - Lung cancer and other malignant diseases involving the lungs
Year: 2008