Intrinsic phenotypic differences of the asthmatic epithelium and its inflammatory responses to RSV and particulate matter

T. L. Hackett, G. Singhera, F. Shaheen, D. Dorsheid, D. Knight (Vancouver, Canada)

Source: Annual Congress 2011 - Lung cell injury and repair
Session: Lung cell injury and repair
Session type: Poster Discussion
Number: 4581
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
T. L. Hackett, G. Singhera, F. Shaheen, D. Dorsheid, D. Knight (Vancouver, Canada). Intrinsic phenotypic differences of the asthmatic epithelium and its inflammatory responses to RSV and particulate matter. Eur Respir J 2011; 38: Suppl. 55, 4581

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Dose-dependent differences of allergic challenge in airway reactivity and BAL cell response
Source: Annual Congress 2008 - Novel therapeutic approaches and immunological mechanisms in airway cell pathobiology
Year: 2008

Different airway inflammatory responses in asthmatic and healthy humans exposed to diesel
Source: Eur Respir J 2004; 23: 82-86
Year: 2004



Environmental particulate matter in induced sputum in airway versus interstitial lung diseases
Source: Eur Respir J 2007; 30: Suppl. 51, 731s
Year: 2007

Airway cells exposed to wildfire smoke extract exhibit dysregulation of autophagy and changes characteristic of inflammatory airway disease.
Source: International Congress 2017 – Current molecular and genetic understanding of lung diseases
Year: 2017

Age-related differences in enhancement of neurogenic airway inflammation and proliferation of airway sensory C-fibers after lipopolysaccharide inhalation in rat pups and adults
Source: Annual Congress 2009 - Mechanisms of pulmonary inflammation and fibrosis
Year: 2009

Airway inflammatory responses to local instillation of fine and coarse ambient particulate matter
Source: Eur Respir J 2004; 24: Suppl. 48, 604s
Year: 2004

Transcriptomic alterations induced by air pollution-derived PM2.5 reflect the shift from healthy to COPD-diseased human bronchial epithelium
Source: International Congress 2018 – Role of omics in population studies
Year: 2018


Evidence for secretion of IL-18 in asthmatic airway inflammation assessed by endobronchial allergen challenge and its relationship to accumulation of inflammatory cells
Source: Eur Respir J 2001; 18: Suppl. 33, 531s
Year: 2001

Baseline airway inflammation may be a determinant of ozone response in asthmatic patients
Source: Annual Congress 2012 - Bronchial challenge as a biomarker of respiratory disease
Year: 2012

Similarities and differences in inflammatory mechanisms of asthma and COPD
Source: Breathe 2011; 7: 229-238
Year: 2011

Fine particulate matter (PM2.5) influence on respiratory tract function and systemic inflammation parameters in healthy adults
Source: International Congress 2019 – Indoor and outdoor air quality considerations
Year: 2019

Increase in markers of airway inflammation after ozone exposure can be observed also in subjects who do not functionally respond to ozone
Source: Eur Respir J 2007; 30: Suppl. 51, 750s
Year: 2007

Molecular response of pulmonary endothelial cells to acute exposure to fine particulate matter
Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases
Year: 2010


Markers of inflammation and airway responses to allergen in asthmatic patients
Source: Annual Congress 2008 - Asthma: growing understanding of influential factors
Year: 2008

Enhanced allergen capture and processing by dendritic cells and other airway APC precedes the onset of allergic airways disease
Source: Annual Congress 2007 - Regulation of allergic airway inflammation in animal models of asthma
Year: 2007


Changes in lung functions and inflammatory markers in induced sputum of patients with bronchial asthma and allergic rhinitis in relation to exposure to pollen allergens
Source: Eur Respir J 2005; 26: Suppl. 49, 734s
Year: 2005

Change of secretory activity of goblet cells of bronchial epithelium in asthma patients in response to cold airway challenge
Source: International Congress 2018 – COPD: novel pathological mechanisms in the airway epithelium
Year: 2018


Comparative responses of upper and lower airway epithelial cells to inflammatory stimulation in COPD
Source: Eur Respir J 2006; 28: Suppl. 50, 338s
Year: 2006

Distribution of the cellular inflammatory pattern in induced sputum in an eosinophilic severe asthma population.
Source: International Congress 2019 – Airway diseases and blood cells
Year: 2019


Exposure to diesel particulate matter enhances the rhinovirus load in primary nasal epithelial cells
Source: International Congress 2017 – Postnatal lung growth and development
Year: 2017