PUR1800 (RV1162), A novel narrow spectrum kinase inhibitor, but not Fluticasone, reduces TNFa-induced cytokine release by primary bronchial epithelial cells from healthy volunteers and COPD patients Source: International Congress 2018 – Preclinical pharmacology: novel targets in airway inflammation, narrowing and neural control Year: 2018
Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells Source: Eur Respir J 2015; 45: 1745-1748 Year: 2015
Syk is downstream of ICAM-1 and mediates human rhinovirus (HRV) activation of p38 MAP kinase in airway epithelial cells Source: Annual Congress 2006 - Airway epithelial cells in inflammation Year: 2006
Interferon-β response to rhinovirus infection in bronchial epithelial cells from asthmatic children Source: Annual Congress 2009 - Epithelial cell biology Year: 2009
Bronchial smooth muscle of severe asthmatic patients decreases rhinovirus replication within the epithelium through a CCL-20/PKR/eIF2-a dependent pathway Source: Virtual Congress 2021 – Asthma treatment: clinical and translational science Year: 2021
Studies into the mechanisms of deficient type I interferon production in asthmatic bronchial epithelial cells Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma Year: 2009
Investigating the effects of interleukin-33 on rhinovirus A induced changes in asthmatic bronchial epithelial cells Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes Year: 2020
Rhinovirus triggers increased inflammasome activation in human bronchial epithelium in asthma. Source: International Congress 2017 – Infection and exacerbation science Year: 2017
The pan janus kinase (JAK) inhibitor KN-002 suppresses inflammatory mediator release from severe asthma bronchial epithelial cells. Source: Virtual Congress 2021 – Airway pharmacology: translational and basic science Year: 2021
Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus Source: Annual Congress 2005 - Environmental factors, allergy and asthma Year: 2005
Protective effect of MAPK inhibitors and budesonide against apoptosis induced by TGF-β in primary cultures of human bronchial epithelial cells Source: Eur Respir J 2003; 22: Suppl. 45, 394s Year: 2003
The potent and lung-selective inhaled pan JAK inhibitor TD-8236 limits airway inflammation without affecting systemic immunity in mice Source: International Congress 2019 – Novel targets and mechanisms in asthma Year: 2019
Effects of respiratory syncytial virus and adenovirus infection in cytokine expression and nuclear factor-κB activation human bronchial epithelial cells Source: Eur Respir J 2006; 28: Suppl. 50, 192s Year: 2006
IL-33 may augment the effect of rhinovirus HRV16 on the inflammatory activity of human lung vascular endothelium – possible implication for asthma exacerbations. Source: Virtual Congress 2021 – New insight into the immunology of allergies, asthma and COPD: from mouse to man Year: 2021
TLR7/8 regulates type I and type III interferon signalling in rhinovirus 1b-induced allergic asthma Source: Eur Respir J, 57 (5) 2001562; 10.1183/13993003.01562-2020 Year: 2021
The influence of allergen challenge on apoptosis and CD-95 receptor level in induced sputum cells from children with bronchial asthma Source: Eur Respir J 2002; 20: Suppl. 38, 6s Year: 2002
Differential effect of fluticasone on Poly(I:C) induced TSLP secretion by bronchial epithelial cells from asthmatic children Source: International Congress 2016 – Mechanisms of disease Year: 2016
How cultured epithelial cells from asthma and COPD patients deal with pathogens: defective anti-rhinovirus responses in asthma Source: Research Seminar 2008 - Host-pathogen interactions in the lung: implications for treatment of respiratory infections and inflammatory lung diseases Year: 2008
Azithromycin augments rhinovirus-induced expression of IFNbeta and IFNλ1 in asthmatic bronchial epithelial cells by up-regulating RIG-I like receptors Source: International Congress 2014 – Novel evidence relating to respiratory treatment development Year: 2014
Rhinovirus up-regulates toll-like receptor 3 on bronchial epithelial cells and is dependent on viral replication Source: Annual Congress 2004 - Mechanisms and treatment of virus induced asthma exacerbations Year: 2004