YKL-40: Novel marker for pro-inflammatory M1 macrophages

L. Kunz, E. van ‘t Wout, A. van Schadewijk, P. Hiemstra (Leiden, Netherlands)

Source: Annual Congress 2011 - Phagocytes and dendritic cells
Session: Phagocytes and dendritic cells
Session type: Thematic Poster Session
Number: 3861
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
L. Kunz, E. van ‘t Wout, A. van Schadewijk, P. Hiemstra (Leiden, Netherlands). YKL-40: Novel marker for pro-inflammatory M1 macrophages. Eur Respir J 2011; 38: Suppl. 55, 3861

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Adiponectin acts as an anti-inflammatory cytokine on human lung macrophages
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Increased TGF-β-inducible early gene (TIEG) in human eosinophils stimulated by Th-2 type inflammatory cytokines
Source: Eur Respir J 2005; 26: Suppl. 49, 659s
Year: 2005

Characterization of M1 and M2 macrophages in human lung tissue
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Airway fibroblasts phenotype markers after pro-inflammatory cytokines challenge
Source: Annual Congress 2009 - Novel mechanisms in the pathogenesis of asthma
Year: 2009


TNF-a and IL-10 control macrophage expression of CXCL13, a prognostic biomarker of idiopathic pulmonary fibrosis
Source: International Congress 2018 – Back to basics and translational research in idiopathic interstitial pneumonias
Year: 2018


Proinflammatory cytokine production during exercise: role of antioxidants and monocytes
Source: Eur Respir J 2002; 20: Suppl. 38, 288s
Year: 2002

Monocyte derived microparticles upregulate IL-8, MCP-1, and ICAM-1 expression by human alveolar epithelial cells
Source: Eur Respir J 2005; 26: Suppl. 49, 26s
Year: 2005

Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9
Source: Eur Respir J 2002; 20: 1198-1205
Year: 2002



Effect of JQ-1 on monocyte-derived macrophage (MDM) phagocytosis of bacteria and cytokine release
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Pro- and anti-inflammatory cytokines TNF-alpha, IFN-gamma, IL-10 and TGF-beta1 levels in blood serum as markers of plasmaferesis success and inflammation activity in lung sarcoidosis (LS)
Source: Eur Respir J 2006; 28: Suppl. 50, 676s
Year: 2006

The pro-resoliving lipid mediator lipoxin A4 inversely correlates with proinflammatory chemokines and identifies a subgroup of asthma patients with disease progression
Source: Virtual Congress 2020 – Novel mechanisms and management of paediatric asthma
Year: 2020


COPD monocytes differentiate into pro-inflammatory macrophages regardless of environment
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013

Cytokine production of alveolar macrophages is decreased by OR2AT4
Source: Virtual Congress 2021 – New insights into the airway immunology of lung disease
Year: 2021


Decreased levels of CXC angiogenic chemokines (IL-8, ENA-78 and GRO-α) in BALF after interferon gamma-1b treatment in IPF patients
Source: Eur Respir J 2005; 26: Suppl. 49, 267s
Year: 2005

Use of interleukin-1beta (IL-1beta) and interleukin-1 receptor antagonist (IL-1Ra) contents in alveolar macrophages for estimation of inflammation activity in patients with different levels of asthma control
Source: Annual Congress 2013 –Macrophages, mononuclear cells and viral infection
Year: 2013


Endotoxin-induced release of the Th17-associated cytokine interleukin (IL)-26 in human neutrophils
Source: International Congress 2017 – Infection and exacerbation science
Year: 2017

Late Breaking Abstract - Bedaquiline enhances receptor phagocytosis and decreases IL1b production in human pro-inflammatory macrophages
Source: Virtual Congress 2021 – Immunological and molecular characterisation of tuberculosis disease and infection
Year: 2021


Increased expression of sphingosine-1-phosphate and S1PR2 are associated with attenuated macrophage phagocytosis in COPD
Source: Annual Congress 2013 –COPD: experimental biology
Year: 2013

Association between proinflammatory cytokines (TNFa and IL8) and fibrinolytic system in malignant pleural effusions
Source: Eur Respir J 2004; 24: Suppl. 48, 494s
Year: 2004

Normal T cell expressed and secreted (RANTES): a marker of asthmatic inflammation?
Source: Eur Respir J 2004; 24: Suppl. 48, 163s
Year: 2004