Short-term exposure to concentrated ambient particles increases airway hyperresponsiveness in normal mice

J. M. Brito, K. Yoshizaki, A. C. Toledo, B. M. Saraiva-Romanholo, A. A. S. Alemany, M. Macchione, P. H. N. Saldiva (São Paulo, Brazil)

Source: Annual Congress 2011 - Environmental exposure and disease mechanisms
Session: Environmental exposure and disease mechanisms
Session type: Poster Discussion
Number: 3319
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. M. Brito, K. Yoshizaki, A. C. Toledo, B. M. Saraiva-Romanholo, A. A. S. Alemany, M. Macchione, P. H. N. Saldiva (São Paulo, Brazil). Short-term exposure to concentrated ambient particles increases airway hyperresponsiveness in normal mice. Eur Respir J 2011; 38: Suppl. 55, 3319

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Increase in markers of airway inflammation after ozone exposure can be observed also in subjects who do not functionally respond to ozone
Source: Eur Respir J 2007; 30: Suppl. 51, 750s
Year: 2007

Maternal allergen exposure increases offspring sensory airway innervation and airway hyperreactivity in mice
Source: International Congress 2018 – Molecular and cellular determinants of the developing lung
Year: 2018

Effects of chronic allergen exposure on the airway hyperreactivity in sensitized rats
Source: Annual Congress 2011 - Animal models of airway inflammation
Year: 2011

Concentrated ambient fine particles (CAPs) elicit airway inflammation and hypersecretory hyperplasia in rats
Source: Annual Congress 2010 - Outdoor air pollution
Year: 2010

Salmeterol has no effect on increased bronchial responsiveness induced by organic dust exposure in healthy volunteers
Source: Eur Respir J 2003; 22: Suppl. 45, 286s
Year: 2003

Attenuated airway hyperresponsiveness and mucus secretion in HDM exposed Igf1r-deficient mice
Source: International Congress 2017 – Postnatal lung growth and development
Year: 2017

Inhalation of nano-scaled titianium dioxide particles aggravates airway inflammation in allergen-challenged mice
Source: Annual Congress 2011 - Environmental exposure and disease mechanisms
Year: 2011


Low dose diesel exhaust particle exposure exacerbates allergic asthma in young mice
Source: Annual Congress 2012 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2012


A role for Th1 cells in airway remodeling and hyperreactivity in mice subjected to chronic allergen exposure
Source: Eur Respir J 2007; 30: Suppl. 51, 734s
Year: 2007

Multiple exposures to swine barn air induce airway hyper-responsiveness and lung inflammation
Source: Eur Respir J 2004; 24: Suppl. 48, 449s
Year: 2004

Diesel exhaust enhances airway responsiveness in asthmatic subjects
Source: Eur Respir J 2001; 17: 909-915
Year: 2001



Intratracheal challenged mice asthma model: can pure low airways inflammation influence the nose?
Source: Annual Congress 2009 - Animal models of airways inflammation
Year: 2009


In vivo blockade of CTLA-4 counteracts inhalation tolerance and leads to development of allergic airway inflammation in mice repeatedly exposed to aerosolized ovalbumin
Source: Eur Respir J 2004; 24: Suppl. 48, 6s
Year: 2004

Inhalation of extrinsic aerosol rIL-10 suppressed eosinophilia in airway of sensitized mice
Source: Eur Respir J 2006; 28: Suppl. 50, 225s
Year: 2006

Fast clearance of inhaled ultrafine particles from airways is reduced in a knockout mouse model with cilia deficiency
Source: Annual Congress 2007 - Advances in respiratory mechanics
Year: 2007


Low exposure to inhaled formaldehyde: effect on allergen bronchial response in asthmatics sensitized to mite
Source: Eur Respir J 2006; 28: Suppl. 50, 592s
Year: 2006

The effects of whole life arsenic exposure via drinking water on airway hyperresponsiveness in C57BL/6 mice
Source: Annual Congress 2011 - Air pollution
Year: 2011


The influence of smoking on the formation of cold airway hyperresponsiveness and destructive-cytolytic profile of goblet cells in asthma patients
Source: International Congress 2018 – Studying novel biomarkers in asthma and COPD
Year: 2018


Repeated exposure to organic material alters inflammatory and physiological airway responses
Source: Eur Respir J 2009; 34: 80-88
Year: 2009



Effects of active and passive smoking on allergic airway inflammation and airway hyperresponsiveness in mice
Source: Eur Respir J 2002; 20: Suppl. 38, 310s
Year: 2002