BMP-Smad1 target gene Wnt inhibitory factor 1 (WIF1) coordinates BMP and Wnt signaling activities in regulating lung development in vivo Source: Annual Congress 2010 - New mechanisms in lung development, acute and chronic lung diseases Year: 2010
AMPK signalling regulates Nrf2 localization and activity via sirtuins in a monocytic cell line Source: Annual Congress 2011 - Recent developments in COPD Year: 2011
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
GCN2 regulates BMP signaling: consequence for PVOD pathobiology and therapeutic management Source: Virtual Congress 2020 – Pathophysiology of pulmonary hypertension Year: 2020
Glucocorticoids promote TGF-β signalling in lung fibroblasts by upregulating ligand and receptor expression, and uncoupling negative-feedback inhibition Source: Annual Congress 2010 - Recent developments of molecular pathology and functional genomics in non-neoplastic and neoplastic lung diseases Year: 2010
Hypoxia-dependent Fhl-1 regulation leads to proproliferative effects in PASMC Source: Annual Congress 2008 - Pathophysiology of pulmonary hypertension Year: 2008
Activation of WNT co-receptor LRP5 is required for WNT and TGF-ß1 induced fibroblast activation Source: Virtual Congress 2020 – Physiological and cellular mechanisms affecting pulmonary pathologies Year: 2020
Stimulation of NOD1 induces RIP2, TAK1 and p38 MAPK dependent pro-inflammatory signalling in human lung microvascular endothelial cells Source: Annual Congress 2011 - Mechanisms of acute lung injury and mesenchymal cell treatment Year: 2011
LSC - 2017 - Profibrotic signaling by TGF-ß involves NADPH oxidase 4 dependent activation of tyrosine kinase Src and mitochondrial ROS Source: International Congress 2017 – Novel pro- and anti-fibrotic mechanisms in pulmonary fibrosis Year: 2017
Reversible repression of IKK by H2 O2 through S-glutathionylation Source: Annual Congress 2005 - Airway epithelial cells in asthma and COPD Year: 2005
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007
Activation of protease-activated receptor 2 elicits epithelial-mesenchymal transition in HBE cells via ROS signaling Source: International Congress 2017 – Therapeutic approaches in lung disease Year: 2017
Thrombin induces stomatin-like protein 2 (STOML2) expression and IL-8/CXCL8 release by ROCK, JNK, and PEA3 pathways in human lung epithelial cells Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms Year: 2020
Insulin-dependent PI3-Kinase/Akt and ERK signaling pathways inhibit TLR3-mediated HBEC apoptosis Source: Annual Congress 2011 - Recent developments in COPD Year: 2011
DTX3L mediated regulation of TBK1 positively regulates type I IFN signalingpathway and cellular antiviral response Source: Virtual Congress 2020 – Different aspects of paediatric viral and bacterial lung infections Year: 2020
Eosinophil adhesion to cholinergic nerve cells induces NFκB activation via the interleukin-1 receptor associated kinase (IRAK) pathway and upregulates ICAM-1 expression Source: Eur Respir J 2003; 22: Suppl. 45, 10s Year: 2003
The pattern recognition receptor Nod1 activates CCAAT/enhancer binding protein β signalling in lung epithelial cells Source: Eur Respir J 2007; 30: 214-222 Year: 2007
Protease activated receptor-1 (PAR-1) stimulation leads to αvβ6 integrin mediated TGFβ activation via rho kinase Source: Eur Respir J 2005; 26: Suppl. 49, 238s Year: 2005
Involvement of NFkB activation and c-JUN phosphorylation in bronchial epithelial cells by CD-40-CD40L pathway Source: Eur Respir J 2002; 20: Suppl. 38, 573s Year: 2002