Molecular mechanism of lung aging in senescence-accelerated mouse (SAM)

Y. Yuan, X. Hu, L. Luo, M. Yang, Z. Su, X. Zhang (Chengdu, China)

Source: Annual Congress 2011 - The ageing pulmonary interstitium
Session: The ageing pulmonary interstitium
Session type: Thematic Poster Session
Number: 795
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Y. Yuan, X. Hu, L. Luo, M. Yang, Z. Su, X. Zhang (Chengdu, China). Molecular mechanism of lung aging in senescence-accelerated mouse (SAM). Eur Respir J 2011; 38: Suppl. 55, 795

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Gene expression and cellular profiling in a rat bleomycin model of drug-induced interstitial lung disease (DIILD)
Source: Virtual Congress 2020 – Mechanistic insight into lung injury and repair
Year: 2020


Structure and function of the newborn mouse versus human infant lung.
Source: International Congress 2017 – Postnatal lung growth and development
Year: 2017

Alteration of ROS metabolism and cell type-specific differentiation markers in the lungs of Pex11β (-/-) mice, a mouse model deficient in peroxisome proliferation
Source: Annual Congress 2008 - Cell biology of asthma and COPD
Year: 2008



Nuclear factor-κB (NF-κβ) activation is associated with susceptibility to urethane-induced lung tumorigenesis in mice
Source: Eur Respir J 2005; 26: Suppl. 49, 225s
Year: 2005

Altered lung developmental pathways during the phase of alveogenesis in mice lacking superoxide dismutase 3, extracellular (SOD3)
Source: International Congress 2014 – Molecular pathogenesis of pulmonary inflammatory diseases (COPD, asthma and ILD)
Year: 2014

Stability of reference genes in five C57/Bl6 models of lung inflammation
Source: Annual Congress 2008 - Inflammatory trigger mechanisms in asthma and COPD
Year: 2008


PBI-compound, a novel first-in-class anti-fibrotic compound, inhibits CTGF and collagen production in murine and human fibroblasts, and reduces lung fibrosis in the bleomycin-induced lung fibrosis model
Source: Annual Congress 2013 –Cell signalling and inflammation: what's new in 2013?
Year: 2013


A potential role for extracellular matrix proteins in lung ageing in COPD
Source: International Congress 2016 – How the understanding og molecular and genomic crosstalk is helping to diagnose lung disease
Year: 2016

Temporal profile of metaloproteases gene expression in elastase-induced emphysema
Source: Annual Congress 2013 –Novel mechanisms in lung injury
Year: 2013

Phosphodiesterase expression profiling in chronic hyperoxia induced lung injury in newborn mice
Source: Annual Congress 2006 - Advances in diagnosis and treatment of pulmonary diseases in children
Year: 2006


Role of peroxiredoxin 6 in lipopolysaccharide-induced mucin production in mice
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

LSC 2011 Abstract: Changes in the proteome upon dermal sensitization in a mouse model of chemical-induced asthma
Source: Annual Congress 2011 - Environmental exposure and disease mechanisms
Year: 2011


Elucidating signalling pathways in pulmonary hypertension using a microRNA knockout mouse model – In vitro and in vivo data
Source: International Congress 2015 – Pulmonary hypertension: rare and hereditary causes of PAH
Year: 2015

LSC 2010 Abstract: The influence of genetic background in a mouse model of chemical-induced asthma
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010

Decreased expression of DNA synthesis repair recombination proteins in lungs of senescence accelerated mouse (SAM)
Source: Eur Respir J 2003; 22: Suppl. 45, 73s
Year: 2003

Enhanced oxidative stress in the lung of klotho mouse, an aging model, as measured by the redox status of coenzyme Q9
Source: Annual Congress 2008 - Phenotyping of asthma and COPD
Year: 2008


Calcium-sensing receptor (CaSR) drives lung ECM remodelling and fibrosis in murine asthma models and in ageing mice
Source: International Congress 2019 – Airway inflammation: pharmacological mechanisms and novel targets
Year: 2019


Can 2,2’-azobis (2-methylpropionamidine) dihydrochloride (AAPH) impair rat lung homeostasis?
Source: Annual Congress 2013 –Various issues in clinical respiratory physiology
Year: 2013


The role of cyclooxygenas-2 in the protection against apoptosis in vascular endothelial cells induced by cigarette smoking
Source: International Congress 2014 – Basic and translational research in asthma and COPD
Year: 2014