Source: Annual Congress 2011 - Exacerbations and severe chronic respiratory disease: oxygen, rehabilitation, admission to hospital and palliative care
Disease area: Airway diseases

Abstract

Background: Depression has been associated with worsening of COPD symptoms and quality of life, more exacerbations and increased mortality.
Objectives: To evaluate prospectively the impact of depressive symptoms on admission on the outcomes of patients hospitalized for COPD exacerbations (ECOPD).
Methods: We studied prospectively 151 patients admitted to hospital for ECOPD. Depression symptoms were evaluated with Becks Depression Inventory. Pulmonary function tests, arterial blood gases and COPD assessment test (CAT) score, were recorded on the day of their admission and 3, 10 and 40 days later. Patients were evaluated monthly for one year.
Results: Duration of hospitalization was longer in patients with high depressive symptoms [5 (3, 6) vs 12 (10, 14), p<0.001]. Furthermore, these patients presented slower recovery from ECOPD as evaluated by improvement in FEV₁, blood gases, dyspnea and CAT score (p<0.001). Patients with more depressive symptoms had more severe disease, according to FEV₁ as well as ADO and DOSE indexes on stability compared to patients with less depressive symptoms (41.5±10.7 vs 62.5±20.0, 4.8± 1.3 vs 4.1±1.2 and 3.5±1.2 vs 1.9±1.2 respectively; p<0.001). During the follow up period, patients with high depressive symptoms had more ECOPD (4.0±1.7 vs 1.2±1.6, p<0.001), shorter time to the next ECOPD and higher one-year mortality (p<0.001). Frequent exacerbators (>2/year) had a higher score in Becks Depression Inventory compared to non-frequent exacerbators (22.2 ±13.1 vs 9.1±4.2 p<0.001).
Conclusions: Depressive symptoms in patients admitted for ECOPD have significant impact on their recovery and are related to worse survival and more new ECOPD during the following year.

Rating:

Share or cite this content

Citations should be made in the following way:
A. Papaioannou, K. Bartziokas, S. Tsikrika, F. Karakontaki, E. Kastanakis, A. Haniotou, V. Poluchronopoulos, K. Kostikas (Athens, Greece). The impact of depression in recovery and outcome of patients hospitalized for COPD exacerbation. Eur Respir J 2011; 38: Suppl. 55, 1254

Member's Comments

No comment yet.

Related content which might interest you: The impact of comorbidities on the short-term serious health outcomes in hospitalized COPD patients due to exacerbation Source: Annual Congress 2013 –COPD treatment and others Year: 2013 The validity of the EQ5D5L in patients hospitalized an acute exacerbation of COPD Source: International Congress 2017 – Latest insights into chronic care Year: 2017 Sit-to-stand ability in patients hospitalised for acute exacerbation of COPD: Clinical characteristics and short-term outcomes Source: International Congress 2015 – New insights into exercise and muscle performance Year: 2015 The impact of depressive symptoms on recovery and outcome of hospitalised COPD exacerbations Source: Eur Respir J 2013; 41: 815-823 Year: 2013 Characteristics and outcome of COPD patients with an acute exacerbation admited to a respiratory ICU Source: Annual Congress 2011 - Intensive care outcome Year: 2011 Quantification of severity of the acute exacerbation in hospitalized COPD patients Source: Eur Respir J 2003; 22: Suppl. 45, 559s Year: 2003 Comparing the prevalence of depression and anxiety in patients admitted with an exacerbation of COPD using two scoring systems Source: International Congress 2015 – Asthma and COPD: overlap and exacerbations Year: 2015 Study of clinical presentation and predictors of adverse outcome in patients admitted for acute exacerbation of COPD. Source: International Congress 2019 – Airway disease-associated exacerbations Year: 2019 The significance of the adherence to the discharge criteria in patients with acute exacerbation of COPD on early readmission Source: International Congress 2017 – COPD management Year: 2017 Influence of previous admissions on audit outcomes in patients admitted with acute exacerbation of COPD (AECOPD) Source: International Congress 2017 – What is new in COPD diagnosis and classification? Year: 2017 Predictors of mortality in COPD patients after hospitalization due to an exacerbation Source: International Congress 2019 – Exacerbations of airway diseases Year: 2019 Effect of depression and anxiety on the risk of exacerbation and hospitalization in COPD Source: Annual Congress 2008 - Epidemiology of respiratory symptoms and COPD Year: 2008 β-blockers and risk of COPD exacerbation requiring hospitalisation in patients with COPD Source: Annual Congress 2011 - Biomarkers and exacerbations of asthma and COPD Year: 2011 Physiological impairments and exacerbation risk in COPD patients with less symptom and no frequent exacerbation history. Source: Virtual Congress 2021 – Prediction of exacerbations in patients with COPD Year: 2021 Prognostic predictors of survival in patients with COPD hospitalized for an acute exacerbation Source: Eur Respir J 2005; 26: Suppl. 49, 284s Year: 2005 Prevalence of heart disease in patients hospitalized for an acute exacerbation of COPD: Impact on clinical outcome. A 6 month follow-up study Source: Annual Congress 2011 - COPD management Year: 2011 Impact of diabetes in patients admitted with acute exacerbation of COPD Source: Annual Congress 2012 - COPD exacerbation Year: 2012 The rationality of the use of NIV in elderly patients with acute COPD exacerbation Source: International Congress 2018 – Non-invasive ventilation for acute respiratory failure Year: 2018 Does airflow limitation severity in stable condition severity of COPD influences in patient cardiac autonomic modulation in COPD patients during hospitalization for exacerbation? Source: Virtual Congress 2020 – COPD phenotypes Year: 2020 Short physical performance battery as a predictor of adverse outcomes following hospitalisation for an acute exacerbation of COPD Source: International Congress 2016 – Management of dyspnoea and exacerbations in chronic lung diseases Year: 2016