Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells

S. K. Biswas, D. McClure, L. L. Jimenez, I. L. Megson, I. Rahman (Edinburgh, United Kingdom; Rochester, United States Of America)

Source: Annual Congress 2004 - Cellular injury and repair in the lung
Session: Cellular injury and repair in the lung
Session type: Oral Presentation
Number: 317

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. K. Biswas, D. McClure, L. L. Jimenez, I. L. Megson, I. Rahman (Edinburgh, United Kingdom; Rochester, United States Of America). Curcumin induces glutathione biosynthesis and inhibits NF-κB activation and interleukin-8 release in alveolar epithelial cells. Eur Respir J 2004; 24: Suppl. 48, 317

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Intracellular thioredoxin mediates inflammatory activation of an alveolar epithelial cell line through activation of NF-κB
Source: Eur Respir J 2003; 22: Suppl. 45, 37s
Year: 2003

Prostaglandin-E2 mediated inhibition of TNFα release from human alveolar macrophages
Source: Eur Respir J 2005; 26: Suppl. 49, 223s
Year: 2005

IL-13 enhances GSNO reductase activity and decreases intracellular S-nitrosothiols in lung epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 103s
Year: 2006

Curcumin restores glucocorticoid function and inhibits cigarette smoke-mediated IL-8 release in oxidant stressed monocytic U937 cells
Source: Eur Respir J 2005; 26: Suppl. 49, 215s
Year: 2005

Histamine-stimulated monocytes release microparticles that upregulate IL-8 synthesis by human alveolar epithelial cells
Source: Eur Respir J 2006; 28: Suppl. 50, 228s
Year: 2006

GB001 potently inhibits PGD2 metabolite-induced DP2-mediated cell signaling and eosinophil activation
Source: Virtual Congress 2020 – Asthma science: novel targets and mechanisms
Year: 2020


VEGF prevents oxidant mediated apoptosis in epithelial cells
Source: Eur Respir J 2005; 26: Suppl. 49, 344s
Year: 2005

Effects of MAPK inhibitors on H2O2-induced IL-8 production and cell death in primary cultures of human bronchial epithelial cells
Source: Eur Respir J 2004; 24: Suppl. 48, 218s
Year: 2004

Cigarette smoke markedly inhibits the LPS-induced production of interleukin-8 in bronchial epithelial cells and consequent neutrophil migration in vitro
Source: Eur Respir J 2004; 24: Suppl. 48, 100s
Year: 2004

N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation
Source: Eur Respir J 2002; 20: Suppl. 38, 170s
Year: 2002

Protein S inhibits the secretion of inflammatory cytokines from alveolar epithelial cells
Source: Annual Congress 2008 - Structural remodelling in COPD
Year: 2008

Inhibition of histone acetyltransferases attenuates cytokine and LPS-induced up-regulation of arginase in rat alveolar macrophages
Source: Eur Respir J 2006; 28: Suppl. 50, 662s
Year: 2006

Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells
Source: Eur Respir J 2002; 20: Suppl. 38, 571s
Year: 2002

Statins suppress LPS-induced proinflammatory cytokine production from human bronchial epithelial cells
Source: Annual Congress 2009 - Epithelial cell biology
Year: 2009


Effects of budesonide on p38 MAPK activation, apoptosis and IL-8 secretion, induced by TNF-alpha and Haemophilus influenzae in human bronchial epithelial cells
Source: Annual Congress 2010 - Regulation of airway pharmacology
Year: 2010

Effects of endothelin-1 on MAPK activation, IL-6 production and cell proliferation in normal human lung fibroblasts
Source: Eur Respir J 2004; 24: Suppl. 48, 454s
Year: 2004

Rhinovirus-induced proinflammatory cascade in bronchial epithelial cells requires xanthine-oxidase system activation
Source: Annual Congress 2008 - New diagnostic methods in viral and atypical infections
Year: 2008


COX-1 driven biosynthesis of PGD2 during activation of human mast cells prevents formation of other prostanoids
Source: Virtual Congress 2020 – Novel molecular markers and targets for asthma phenotypes
Year: 2020


CCL5 (RANTES) inhibits TGF-β1-induced collagen production in human bronchial epithelial cells by action of Smad protein
Source: Annual Congress 2009 - New results in molecular pathology and functional genomics of non-neoplastic lung diseases
Year: 2009

SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescence
Source: Annual Congress 2011 - Epithelial cells: role in health and disease
Year: 2011