Source: Annual Congress 2004 - Improved understanding of the basic mechanisms impact on the management of COPD
Disease area: Airway diseases



Rating:

Share or cite this content

Citations should be made in the following way:
R. A. Clayton, A. Mackenzie, C. A. J. Dick, S. F. Hastings, A. Cooreman, V. Anikin, S. J. MacKenzie (Glasgow, Bradford, United Kingdom). Phosphodiesterase expression and activity in human airways. Eur Respir J 2004; 24: Suppl. 48, 266

Member's Comments

No comment yet.

Related content which might interest you: PDE isozymes and effects of selective PDE inhibitors on human lung fibroblasts (Fbs) Source: Eur Respir J 2005; 26: Suppl. 49, 551s Year: 2005 Effects of PDE4 inhibitors on eotaxin-3 (CCL26) expression in lung epithelial cells Source: Annual Congress 2009 - Epithelial cell biology Year: 2009 The PDE4 inhibitor roflumilast N-oxide partly reversed TGFß1-induced changes in collagen I and E-cadherin expression in human airway epithelial cells Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD Year: 2008 TGF-β modulates Na+,K+-ATPase expression and activity in the lung epithelium Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury Year: 2008 Inhibition of phosphodiesterase 4B enhances glucocorticoid-dependent gene transcription in human airway epithelial cells: Implications for the treatment of COPD Source: Annual Congress 2013 –New drugs in respiratory medicine Year: 2013 Upregulation of smooth muscle Rho-kinase protein expression in human asthma Source: Eur Respir J, 55 (3) 1901785; 10.1183/13993003.01785-2019 Year: 2020 Characterisation of eppin function: expression and activity in the lung Source: Eur Respir J, 50 (1) 1601937; 10.1183/13993003.01937-2016 Year: 2017 MAP kinase phosphatase 1 mediates glucocorticoid inhibition of CD38 expression in human airway smooth muscle Source: Annual Congress 2008 - Basic science in asthma and COPD II Year: 2008 Phosphodiesterase 4 and 5 inhibitors decrease HO-1 and IL-8 gene expression induced by cigarette smoke Source: Annual Congress 2008 - Pathophysiology of pulmonary hypertension Year: 2008 The novel phosphodiesterase 4 inhibitor CI-1044 inhibits in vitro LPS-induced TNFα production in whole blood of COPD patients Source: Eur Respir J 2001; 18: Suppl. 33, 34s Year: 2001 IL-13 induces glucocorticoid resistance in iNOS expression and activity in human airway epithelial cells (HAECs) Source: International Congress 2017 – New insights into pathogenesis of lung disease  Year: 2017 The combination of PDE4 and PDE5 inhibitors reduces YAP expression in IPF Source: International Congress 2017 – Towards better treatments for lung disease: experimental pharmacology Year: 2017 Effects of phosphodiesterase-4 inhibitors on surfactant protein-A expression in adult alveolar epithelial cells type II Source: Annual Congress 2007 - Epithelial networks in the airways Year: 2007 Metformin regulates sirtuin expression in airway epithelial cells Source: International Congress 2018 – New kids on the block: novel molecular pathways and therapeutic targets in chronic lung diseases Year: 2018 Therapeutic potential of a new phosphodiesterase inhibitor in acute lung injury Source: Eur Respir J 2003; 22: 20-27 Year: 2003 LSC 2010 Abstract: Experimental asthma: expression and activation of protein kinase C isoenzymes in airway smooth muscles (ASM) & lymphocytes and structural changes in lung tissues during the development of airway hypersensitivity in guinea pig model of asthma Source: Annual Congress 2010 - COPD and asthma: models and human studies Year: 2010 PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity Source: ERS Lung Science Conference 2021 Year: 2021 Anti-inflammatory effect of bosentan on endothelin-1- and TNF-α-induced GMCSF expression in human airways smooth muscle cells – role of MAPkinases ERK-1,-2 Source: Annual Congress 2007 - Inflammatory cell biology Year: 2007 Effects of pendrin inhibitor (PDI_C01) in vitro, and in vivo models of lipopolysaccharide-induced airway inflammation. Source: International Congress 2019 – Biomarkers, laboratory findings and pre-clinical data in acute respiratory failure Year: 2019 Gene transfer of a β-adrenergic receptor kinase inhibitor up-regulated levels of β-adrenergic receptor and cAMP in asthmatic murine lung Source: Eur Respir J 2005; 26: Suppl. 49, 580s Year: 2005