A novel therapeutic approach to airway inflammation using filarial nematode derived ES-62

C. McSharry, M. Patel, P. Kewin, D. Kean, R. Chaudhuri, Y. Bordon, M. M. Harnett, N. C. Thomson, W. Harnett (Glasgow, United Kingdom)

Source: Annual Congress 2004 - Modulation of the allergic response in animal models
Session: Modulation of the allergic response in animal models
Session type: Oral Presentation
Number: 166
Disease area: Airway diseases

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. McSharry, M. Patel, P. Kewin, D. Kean, R. Chaudhuri, Y. Bordon, M. M. Harnett, N. C. Thomson, W. Harnett (Glasgow, United Kingdom). A novel therapeutic approach to airway inflammation using filarial nematode derived ES-62. Eur Respir J 2004; 24: Suppl. 48, 166

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Macrophage migration inhibitory factor (MIF)-like protein isolated from whale roundworm larva inhibits airway inflammation in a murine model of asthma
Source: Eur Respir J 2006; 28: Suppl. 50, 358s
Year: 2006

Early Ascaris suum migration in mice induces eosinophils airway inflammation and hyperresponsiveness
Source: Eur Respir J 2005; 26: Suppl. 49, 587s
Year: 2005

Helminth extract from opisthorchis felineus suppresses allergic inflammation through modulation of dendritic cells phenotype
Source: Annual Congress 2012 - Mechanisms and modulation of allergic inflammation in the lung
Year: 2012


Exposure to helminth parasites and asthma development
Source: International Congress 2019 – Infections, the microbiome and host defence peptides in the development and progression of asthma
Year: 2019


Immunotherapy improves inflammatory response and lymphocyte apoptosis as a new therapeutic target in sepsis rat
Source: Annual Congress 2009 - Severe sepsis and multiple organ failure
Year: 2009


How does the gut microbiota regulate immune responses in the airways?
Source: Annual Congress 2006 - Can environmental exposures prevent allergic disease, what are the mechanisms and how important is timing of exposure?
Year: 2006


Characterisation of type two immune responses in a murine model of allergic airway disease
Source: Virtual Congress 2020 – Scientific advances in airway pharmacology
Year: 2020


Neu-164, a novel antioxidant and anti-inflammatory compound reduces lung inflammation in a murine model of allergic asthma
Source: Annual Congress 2008 - Comorbid cardiovascular condition and therapy of asthma
Year: 2008

T-cell co-stimulatory molecules: novel targets for the treatment of allergic airway disease
Source: Eur Respir J 2007; 30: 383-390
Year: 2007



Soluble ADAM33 augments the pulmonary innate immune response promoting susceptibility to allergic airway inflammation
Source: International Congress 2018 – Translational models of the immunopathology that underlies airway obstructive diseases
Year: 2018


IL-10 is not essentially involved in the mechanism of pulmonary allergic response inhibition in mice exposed to angiostrongylus costaricensis extract
Source: Annual Congress 2008 - Understanding allergic airway inflammation with the help of animal models
Year: 2008

A novel immune regulatory function of neutrophils in rhinovirus infections
Source: Lung Science Conference 2015
Year: 2015




Experimental specific immunotherapy with timpol decreases allergic sensitization and airway inflammation in murine model of bronchial asthma
Source: Annual Congress 2010 - Animal models of asthma and lung inflammation
Year: 2010


ST2 gene knockout attenuates allergic airways disease
Source: Annual Congress 2006 - Immunological mechanisms in cell recruitment to the lungs
Year: 2006


Mucosal cryobiopsies – a new method for studying airway pathology in asthma
Source: Virtual Congress 2021 – Bronchoscopy in the COVID - 19 era: cryobiopsy
Year: 2021


Effect of distinct parasite extracts on pulmonary allergic response in mice
Source: Annual Congress 2008 - Understanding allergic airway inflammation with the help of animal models
Year: 2008

The potential role of antimicrobial peptides from wasp as regulators of the fibrotic process in idiopathic pulmonary fibrosis.
Source: International Congress 2019 – Assessment and management of immune-mediated interstitial lung diseases
Year: 2019

Anti-cytokine approaches should target bronchial hyperresponsiveness rather than inflammation – Pro
Source: Annual Congress 2006 - Pro/Con: asthma is (not) an inflammatory disease
Year: 2006