Susceptibility to tobacco smoke related to protease inhibitor PIM subtypes in COPD Source: Annual Congress 2005 - What's new in tobacco and lung disease Year: 2005
A combination of erythromycin and dexamethasone reduces inflammatory effects of exposure to cigarette smoke extract through modulation of Akt and histone deacetylase 2 Source: International Congress 2014 – Clinical problems in acute and chronic lung diseases Year: 2014
Inhibition of lung inflammation by a protein epitope mimetic (PEM) neutrophil elastase inhibitor, POL6014, in a sub-chronic tobacco smoke (TS) model in mice Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD Year: 2013
Increased proportion of slow decliners in patients with alpha-1 protease inhibitor (A1-PI) deficiency following treatment with A1-PI Source: International Congress 2016 – New and old therapies for chronic lung diseases Year: 2016
LSC Abstract – A functional variant of secretory leukocyte protease inhibitor (SLPI) with improved anti-inflammatory activity against pulmonary infection Source: International Congress 2015 – Immunomodulation: basic science and clinical aspects Year: 2015
A functional variant of secretory leukocyte protease inhibitor (SLPI) with improved anti-inflammatory activity against pulmonary infection Source: Lung Science Conference 2015 Year: 2015
A selective MMP-12 inhibitor, MV062926, reduces inflammatory responses to cigarette smoke in mice Source: Annual Congress 2010 - Pre-clinical models of airways disease Year: 2010
Increased detection of interleukin-;5 in sputum by addition of protease inhibitors Source: Eur Respir J 2001; 18: 685-691 Year: 2001
The combination of TNF-α neutralization and dexamethasone treatment restored the corticosteroid responsiveness in tobacco smoking mice Source: International Congress 2016 – Airway pharmacology: drug targets and mode of action Year: 2016
Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice Source: Eur Respir J 2006; 27: 1102-1109 Year: 2006
Potent anti-inflammatory effects of the highly selective iNOS inhibitor Byk402750 in a mouse model of cigarette smoke induced inflammation Source: Annual Congress 2008 - Novel experimental approaches to understanding asthma and COPD Year: 2008
Ensifentrine, a dual PDE3/PDE4 inhibitor, improves FEV1 regardless of smoking status or history of chronic bronchitis Source: Virtual Congress 2020 – Cutting edge science: novel molecules and mechanisms of airway diseases Year: 2020
BmTI-A, a serine protease inhibitor, reduces the chronic allergic lung inflammation in a mice model Source: International Congress 2015 – Novel treatments for cough, asthma, COPD and bronchiectasis Year: 2015
Therapeutic neutralization of the matrikine PGP suppresses the development of lung emphysema in cigarette smoke exposed mice Source: International Congress 2016 – Mechanisms of disease Year: 2016
Pharmacological profile and efficacy of GLPG1690, a novel ATX inhibitor for COPD treatment Source: International Congress 2015 – New targets and modalities for the treatment of asthma and COPD Year: 2015
Macrophage chromatin condition and protease inhibitor activity studying in brush-biopsies at patients with infectious COPD exacerbation Source: Eur Respir J 2007; 30: Suppl. 51, 142s Year: 2007
Impact of polymorphisms in genes involved in nicotine dependence pathways on the smoking burden of COPD patients Source: International Congress 2019 – New molecular signatures in COPD, lung cancer and a1-antitrypsin deficiency Year: 2019
COPD non-exacerbator phenotype is associated with current smoking but not with Haptoglobin phenotype Source: International Congress 2017 – Airway disease and exacerbations Year: 2017
Women and lung cancer: potential mechanisms of greater susceptibility to tobacco smoke Source: ISSN=1025-448x, ISBN=1-904097-28-6, page=146 Year: 2003
Human airway trypsin-like protease stimulates protease activated receptors and interactions of these receptors Source: International Congress 2019 – Immunopathological mechanisms of lung disease Year: 2019