Source: Annual Congress 2005 - Biological and treatment aspects of tuberculosis
Disease area: Respiratory infections

Abstract

Aim: to identify the risk factors for default in new pulmonary TB cases. The experience of the first Romanian DOTS pilot project, developed in Iasi County, Romania, showed that between 1998-2003 26 patients defaulted yearly from the first TB treatment.
Method: a comparative retrospective study of different characteristics in 2 samples of new pulmonary TB cases, with the same demographic characteristics was done.
Results: relevant differences between factors who could determine the default were: unemployment (p<0.0001), homeless (p<0.0001), the marital status -(p<0.01), low levels of education (p<0.0001), a longer time of hospitalization, other associated diseases-specially alcoholism-(p<0.0001), 62% patients defaulted in the continuation phase; 60% of the patients returned for treatment; 77.7% were finally successfully treated, 18.5% defaulted again and 3.3 %died.
Conclusions:
The key risk factors associated with default are sex male, alcoholism, unemployment and homeless.
The socio-economic characteristics had the strongest influence for default; their earlier detection and evaluations could be used to prevent the default in the future.

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Citations should be made in the following way:
A. Sorete-Arbore, V. Cojocariu, T. Mihaescu (Iasi, Romania). Risk factors for the default from DOTS - experience of the Iasi County, Romania. Eur Respir J 2005; 26: Suppl. 49, 2911

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