TGFβ overproduction in asthma reduces the epithelial repair by down-regulating the leptin/leptin receptor pathway Source: Eur Respir J 2007; 30: Suppl. 51, 59s Year: 2007
Synergistic action of formoterol on budesonide-generated decrease of proteoglycan production by activated lung fibroblasts is mediated via β-adrenergic receptor and is dependent on glucocorticoid receptor Source: Eur Respir J 2004; 24: Suppl. 48, 345s Year: 2004
Growth hormone releasing hormone-receptor antagonist MIA-602 modulates lung inflammation, cellular signal transduction, and promotes apoptosis of mouse lung fibroblasts Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020
PP216 – Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity Source: ERS Lung Science Conference 2021 Year: 2021
Endothelin-1 activates pro-inflammatory signalling pathway via destinct p38MAPK isoforms resulting in downregulation of nuclear p27kip1 Source: Annual Congress 2009 - Airway cell biology Year: 2009
G-protein mediated EGFR transactivation induces mucin production Source: Annual Congress 2003 - Cellular and molecular mechanisms in epithelium injury and repair Year: 2003
Differential role of EPAC and PKA in the transduction of cAMP-mediated inhibition of human lung fibroblast proliferation and collagen synthesis Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation Year: 2009
Bile acid receptor accelerates to the lung cancer process induced by lung fibroblast-tumor cells interaction, with high activation of phosphorylated STAT3 and alteration of cytokine secretion Source: International Congress 2017 – Lung cancer - basic science: the latest results from the bench Year: 2017
The muscarinic receptors promote IL-8 release in airway epithelial cells via the pERK42/44 and NF-kB pathways Source: Eur Respir J 2006; 28: Suppl. 50, 746s Year: 2006
Muscarinic receptors mediate up-regulation of endothelin-1 expression in human lung fibroblasts Source: Annual Congress 2010 - Regulation of airway pharmacology Year: 2010
Oral Presentation: The functional role of the Frizzled-8 receptor TGF-beta1-induced activation and extracellular matrix production in human lung fibroblasts Source: Lung Science Conference 2012 - Rebuilding a diseased lung: Repair and regeneration Year: 2012
Endotoxin induces proliferation of NSCLC cells by a COX-2 dependent manner – Role of CD14, TLRs and EGFR signaling Source: Annual Congress 2010 - Pathology of lung cancer Year: 2010
The expression of muscarinic receptors is involved in the p42/44ERK and NF-kB activation of human lung fibroblasts from COPD subjects Source: Eur Respir J 2006; 28: Suppl. 50, 102s Year: 2006
Decreased PTEN amplifies PI3K signaling and enhances pro-inflammatory cytokine release in COPD Source: International Congress 2016 – Studies in airway cell biology Year: 2016
SiRNA mediated growth factor receptors inhibition in A549 cell model of lung cancer gene therapy: insulin-like growth factor-I receptor (IGF-R1) blockade produces changes that potentially induce anti-tumor immunity Source: Annual Congress 2008 - Biology in thoracic tumours Year: 2008
TGFβ induced myofibroblast differentiation is independent of p38 activation, but requires TGFβR1 kinase activity and correlates with TGFβ-mediated SMAD signaling and TGFβ-responsive gene expression patterns in human lung fibroblasts Source: Eur Respir J 2004; 24: Suppl. 48, 718s Year: 2004
Toll-like receptor stimulation induces airway hyperresponsiveness to bradykinin, an effect mediated by JNK and NF-κB signaling pathways Source: Eur Respir J 2005; 26: Suppl. 49, 732s Year: 2005
6-aminonicotinamide ameliorates pulmonary fibrosis by suppressing the TGF-beta1 activated Smad signalling pathway Source: Virtual Congress 2020 – Translational therapeutic advances Year: 2020
Inhibition of VEGF blocks the activation of TGF-β1 through a PI3K/Akt signaling pathway in allergic airway disease of mice Source: Annual Congress 2007 - Current issues in airway physiology, pharmacology and monitoring Year: 2007