Source: Annual Congress 2010 - Nocturnal cardiology: chronic heart failure, acute chest syndrome, coronary artery disease and collagen vascular disease
Disease area: Sleep and breathing disorders

Abstract

Background: Polysomnography (PSG) is considered the gold standard diagnostic test for sleep apnea syndrome (SAS), however due to its complexity, it is not easily accessible. On the other hand, patients (pts) with acute coronary syndrome (ACS) have higher prevalence of SAS and were rarely performed screening of SAS in coronary care unit (CCU).
Objectives: To evaluate: 1) prevalence of SAS in pts admitted with ACS in CCU 2) clinical predictors of SAS in pts with ACS 3) results of a dual bioparameter monitoring device for SAS with PSG.
Methods: Prospective study including consecutive pts admitted in CCU with ACS with coronary disease confirmed by coronary angiography. Demographic and anthropomorphic data, cardiovascular risk factors and Epworth Sleepiness Scale (ESS) were collected. A sleep study conducted with the Apnea LinkTM (AL) during hospitalization or after discharge. It was considered diagnosis of SAS for an apnea-hypopnea index (AHI) ≥ 5 by AL. Pts with AHI ≥ 10 by AL were submitted to PSG.
Results: The study included 58 patients, 43 (74%) were male, the mean age was 62 ± 12 years and the mean BMI was 27 ± 3 kg/m2. AL classified 21 pts on mild SAS and 16 pts on moderate-severe SAS. Pts with SAS had a higher score of ESS (P=0,019), and history of chronic angina (P=0,043). 22 out of 25 pts with AHI ≥ 10 by AL were submitted to PSG. PSG confirmed the severity of all the patients with moderate-severe SAS by AL. Cheyne-stokes pattern were detected on 8 pts by PSG.
Conclusions: In our study we found a high prevalence of SAS in patients hospitalized with ACS, 27,6% have moderate-severe SAS. A dual bioparameter monitoring device during sleep may play a role in screening and evaluation of patients with ACS.

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Citations should be made in the following way:
K. Cunha, V. Areias, J. Romero, R. Faria, J. Mimoso, V. Gomes, U. Brito (Portugal). Screening of sleep apnea syndrome in patients with acute coronary syndrome. Eur Respir J 2010; 36: Suppl. 54, 910

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