Relationship between dyspnea, exercise performance, pulmonary functions, and peripheral muscle strength in patients with pulmonary hypertension

R. Demir, H. N. Gurses, S. Ozyilmaz, G. M. Dogan, M. S. Kucukoglu (Turkey)

Source: Annual Congress 2010 - Exercise training: new groups, new methods and outcomes
Session: Exercise training: new groups, new methods and outcomes
Session type: Thematic Poster Session
Number: 4886
Disease area: Pulmonary vascular diseases

Congress or journal article abstract

Abstract

Aim: In this study we aimed to evaluate the relationship between Medical Research Council (MRC) dyspnea scale, exercise performance, pulmonary functions, respiratory and peripheral muscle strength in patients with pulmonary arterial hypertension (PH).
Methods: 36 patients (22F/14M; mean age 42.3 yrs) with PH were studied. Exercise performance was determined by using six minute walking test (6MWT). Pulmonary functions, respiratory muscle strength (maximal inspiratory (MIP) and maximal expiratory (MEP) pressure) and peripheral muscle strength (handgrip strength) were measured. Level of dyspnea was evaluated with MRC dyspnea scale. The data were analyzed by nonparametric correlations (Spearman rank correlation coefficient).
Results: The mean (sd) MRC dyspnea score was 2.9 (1.1). We found statistically significant correlations between MRC and 6MWT distance (r=-0.56, p=0.0004), FVC (r=-0.39, p=0.02), FVC% (r=-0.34, p=0.04), FEV1 (r=-0.45, p=0.005), FEV1% (r=-0.44, p=0.007), FEV1/FVC (r=-0.33, p=0.05), FMF (r=-0.42, p=0.01), FMF% (r=-0.42, p=0.01), PEF (r=-0.60, p=0.0001), PEF% (r=-0.48, p=0.004), MEP (r=-0.54, p=0.0007), handgrip strength (r=-0.35, p=0.03).
Conclusion: Our results showed that the increase in dyspnea score is related with the decrease in exercise performance, pulmonary functions, expiratory muscle strength and peripheral muscle strength in patients with PH.


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R. Demir, H. N. Gurses, S. Ozyilmaz, G. M. Dogan, M. S. Kucukoglu (Turkey). Relationship between dyspnea, exercise performance, pulmonary functions, and peripheral muscle strength in patients with pulmonary hypertension. Eur Respir J 2010; 36: Suppl. 54, 4886

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