Source: Annual Congress 2010 - Exercise training: new groups, new methods and outcomes
Disease area: Airway diseases

Abstract

Background: Chronic obstructive pulmonary disease (COPD) affects lung function, exercise capacity and health-related quality of life (HRQoL). Pulmonary rehabilitation (PR) improves exercise capacity and HRQoL, but the long-term effects of PR are difficult to value against the progressive nature of COPD. The aim of this study was to evaluate patients with COPD, five years after PR.
Methods: Out of 89 patients at Uppsala University Hospital, 59 patients were followed-up. Twenty-one patient (24%) had died. Patients had GOLD stage III-IV when enrolled in PR (FEV₁ 34 ± 12 % pred.) and their mean age was 63 ± 7 years. Lung function, 12-minute walk distance (12MWD) and HRQoL (SF-36), anxiety, and depression (HAD) and dyspnoea (CRDQ) were measured.
Results: Sixteen patients had continued exercising at least once a week for at least one year after PR. Fifteen (25%) had got additional diagnosis that affected their exercise capacity negatively. The 12MWD had decreased by 143m (16%), vital capacity by 0,33 L (10%) and diffusion capacity (DL_CO) by 13 µmol/sec/kPa (21%). FEV₁ (liters) had not decreased. Anxiety and dyspnoea increased by 5% and 12% respectively, depression and HRQoL were unchanged. The change in DL_CO and dyspnoea related significantly to the decline in 12MWD, although only with r² = 0,18 (p< 0,05) and 0,35 (p<0,001), respectively.
Conclusions: Mortality and additional morbidity was high and 12MWD decreased in survivors during five-year follow-up after PR. Except for FEV₁, lung function declined, but could not explain the decline in 12MWD.

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Citations should be made in the following way:
H. Arnardóttir, C. Janson, H. Hedenström, M. Emtner (Uppsala, Sweden; Akureyri, Iceland). Five years follow-up after pulmonary rehabilitation of patients with COPD. Eur Respir J 2010; 36: Suppl. 54, 4868

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