Blocking VEGF does not induce proapoptotic effects in the NSCLC cell line A549

C. Wohlkoenig, K. Leithner, A. Hrzenjak, A. Olschewski, H. Olschewski (Austria)

Source: Annual Congress 2010 - New insights in the pathology of lung cancer
Session: New insights in the pathology of lung cancer
Session type: Oral Presentation
Number: 5169
Disease area: Pulmonary vascular diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. Wohlkoenig, K. Leithner, A. Hrzenjak, A. Olschewski, H. Olschewski (Austria). Blocking VEGF does not induce proapoptotic effects in the NSCLC cell line A549. Eur Respir J 2010; 36: Suppl. 54, 5169

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Downregulation of expression growth factor receptor induced by vector-based siRNA and its effect on radiosensitivity of pulmonary adenocarcinoma cell line
Source: Eur Respir J 2006; 28: Suppl. 50, 810s
Year: 2006

Functional expressions of EGFP/LKB1 and its kinase domain induced apoptosis and enhanced chemosensitivity in lung cancer cell lines
Source: Eur Respir J 2004; 24: Suppl. 48, 5s
Year: 2004

Specific plasmids encoding shRNA molecules directed against growth factor receptors in cell proliferation inhibition and induction phenotype changes relevant to enhancement of anti-tumor immunity. Model of human non-small (NSCLC) and small (SCLC) cell lung cancer lines
Source: Annual Congress 2010 - Pathology of lung cancer
Year: 2010

Magnolol can induce apoptosis in non-small cell lung cancer via caspase-independent pathway
Source: Annual Congress 2011 - Biomarkers and other new methods for lung cancer
Year: 2011

Salinomycin suppresses TGF-ß1-induced EMT by down-regulating MMP-2,9 via AMPK-SIRT1 pathway in a non-small cell lung cancer
Source: International Congress 2017 – Basic research in lung cancer: a scientific potpourri from genetic alterations to immune cells
Year: 2017

Bcl-2 overexpression inhibits apoptotic cell death, but is not sufficient to protect L929 cells from hyperoxia
Source: Eur Respir J 2005; 26: Suppl. 49, 345s
Year: 2005

Leptin and apigenin: antagonists in the apoptotic pathway of lung adenocarcinoma cell line
Source: Eur Respir J 2006; 28: Suppl. 50, 668s
Year: 2006

KPNB1-mediated PD-L1 nuclear translocation promotes non-small cell lung cancer cell proliferation via the Gas6/MerTK signalling pathway
Source: Virtual Congress 2020 – Biological mechanisms of lung cancer
Year: 2020

Inhibition of insulin-like growth factor type I (IGF-I) gene in A549 human lung cancer cell line enhances cell apoptosis and causes phenotype changes relevant to increased tumor susceptibility to immune system
Source: Eur Respir J 2007; 30: Suppl. 51, 715s
Year: 2007

Effects of p27Kip1 on cell cycle status and viability in A549 lung adenocarcinoma cells
Source: Eur Respir J 2004; 23: 665-670
Year: 2004



A549 cell promotes the proliferation and migration of fibroblast through FXR pathway
Source: International Congress 2019 – Biology of lung cancer
Year: 2019

Inhibitory effects of shRNA targeting layilin on adhesion and invasion behavior of human lung carcinoma cell A549 induced by hyaluronan in vitro
Source: Eur Respir J 2006; 28: Suppl. 50, 855s
Year: 2006

Inhibition of B7-H4 gene expression by RNA interference (RNAi) in lung cancer A549 cell line
Source: Annual Congress 2011 - Progress in pathology of lung cancer
Year: 2011

The effects of TNF-α combined with VP16 on growth and cell cycle of lung cancer cell line and the adhesive molecules
Source: Eur Respir J 2002; 20: Suppl. 38, 73s
Year: 2002

Alpha1-antitrypsin inhibits staurosporine-induced apoptosis of NSCLC cells
Source: Virtual Congress 2020 – Biological mechanisms of lung cancer
Year: 2020


Caspase recruitment domain containing protein 9 suppresses non-small cell lung cancer proliferation and invasion via inhibiting MAPK/p38 pathway
Source: Virtual Congress 2020 – Molecular alterations and immunology in lung cancer
Year: 2020

Adenovirus-mediated E2F-1 gene transfer in nonsmall-cell lung cancer induces cell growth arrest and apoptosis
Source: Eur Respir J 2002; 20: 703-709
Year: 2002



Adenovirus-mediated AP-2α down-regulates MnSOD expression in lung cancer A549 cells and its molecular mechanism
Source: Annual Congress 2011 - Progress in pathology of lung cancer
Year: 2011

Inhibitory effects of shRNA targeting twist on epithelial-mesenchymal transition and invasion ability of human lung carcinoma cell A549 in vitro
Source: Eur Respir J 2006; 28: Suppl. 50, 325s
Year: 2006

HIF-1α modulation by topoisomerase inhibitors in A549, a non-small cell lung cancer cell line
Source: Annual Congress 2007 - Biology in thoracic oncology
Year: 2007