Source: Annual Congress 2010 - COPD: treatment and monitoring
Disease area: Airway diseases

Abstract

INTRODUCTION:
Karnofsky index has been used to measure the clinical and functional status in hospitalized patients. The main topic of this study is to assess if this index determines the number of admissions, emergency visits, and mortality in a short and medium term, in patients with moderate and severe COPD (classified by GOLD).
METHODS:
52 moderate or severe COPD patients were included and monitored during 3 months. The variables studied were: age, sex, hospitalization days, tobacco consum, number of emergency visits, hospital readmissions and NIMV treatment.
RESULTS:
The 85% who have been studied were men and 15% were women. The averge men age was 69 years and 78 for women. The average hospitalization days was 12,5 (range 3-72). 61% were diagnosed as moderate COPD and the 39% were diagnosed as severe COPD. 42% obtained more than 60 points in Karnofsky index and 58% less than 60. Considering the smoking habits 60% were active smokers and 30% had been smoker previously. The overage index packages was 43±36 per year. 34% re-entered at the Pneumology Department at least once for COPD exacerbation, and 41% visited Urgencies at least once for the same reason. There was a 17% of mortality during their time at hospital and the following three months.
There are stadistical differences between a hirgher mark than 60 points in Karnofsky Index and the number of visits at Emergences and readdmitions for COPD exacerbations. The patients who had a Karnofsk Index higher than 60%, suffered a higher mortality than the rest.
CONCLUSIONS:
Karnofsky index is a good prognostic predictor of mortality, hospitalizations and emergency visits for exacerbation for severe and moderate COPD patients.

Rating:

Share or cite this content

Citations should be made in the following way:
L. Anoro, E. Tieso, F. Campo, D. Morillo, C. Gonzalez, A. Pérez (Zaragoza, Spain). Karnofsky index as predictor of exacerbations in moderate and severe COPD patients. Eur Respir J 2010; 36: Suppl. 54, 1326

Member's Comments

No comment yet.

Related content which might interest you: BODE index as predictor of exacerbation occurrence in ambulatory patients with COPD Source: Annual Congress 2007 - Exacerbations of COPD Year: 2007 ²DOSE² index in severe COPD Source: Eur Respir J 2007; 30: Suppl. 51, 97s Year: 2007 Impact of moderate and severe exacerbations in severe COPD patients Source: International Congress 2018 – How far are we in terms of predicting mortality and exacerbations in COPD? Year: 2018 Change in BODE index, exacerbation duration and hospitalisation in a cohort of COPD patients Source: Annual Congress 2008 - Prognosis in COPD Year: 2008 Predictors of severe exacerbations in patients with moderate and severe asthma Source: International Congress 2018 – Determinants and monitoring of asthma control Year: 2018 Fatigue in COPD: association with functional status and hospitalisations Source: Eur Respir J 2013; 41: 565-570 Year: 2013 GOLD staging and grading for predicting one-year mortality in COPD patients with severe exacerbation Source: International Congress 2016 – Biomarkers and phenotypes of COPD Year: 2016 The derivation of a new index of severity for COPD patients, the DOSE index: MRC dyspnea scale, airflow obstruction, smoking status and exacerbations Source: Annual Congress 2007 - Predicting factors of patients undergoing rehabilitation Year: 2007 Compliance index among patients with mild asthma Source: Annual Congress 2008 - Comorbid cardiovascular condition and therapy of asthma Year: 2008 The EQ-5D is responsive to recovery from a moderate COPD exacerbation Source: Annual Congress 2009 - Quality of life and symptoms in COPD Year: 2009 Low hematocrit as predictor of exacerbation frequency in COPD patients Source: Annual Congress 2010 - Exacerbations and COPD and rehabilitation Year: 2010 Both moderate and severe exacerbations accelerate physical activity decline in COPD patients Source: Eur Respir J, 51 (1) 1702110; 10.1183/13993003.02110-2017 Year: 2018 Fibrinogen, health status and hospitalization in patients with moderate to severe COPD Source: Annual Congress 2011 - COPD mechanisms Year: 2011 Daily symptom burden in patients with severe COPD Source: Annual Congress 2010 - Palliative care, oxygen and community care for chronic lung disease Year: 2010 APACHE II and MPMo scores in prediction of outcomes in patients with severe exacerbation of chronic obstructive pulmonary disease Source: Eur Respir J 2002; 20: Suppl. 38, 83s Year: 2002 Poor quality of life is associated with frequent exacerbations in moderate-to-severe COPD patients Source: Eur Respir J 2001; 18: Suppl. 33, 190s Year: 2001 A Comparison of three severity assessment scores: APACHI II SOFA and CURB 65 for predicting inpatient mortality in patients with acute exacerbation of COPD (AECOPD) Source: International Congress 2015 – Acute critical care: COPD, muscles and weaning Year: 2015 The relation of comorbidities with the exacerbation severity in patients with COPD Source: Annual Congress 2013 –COPD mechanisms Year: 2013 Walking distance is a predictor of exacerbations in patients with COPD Source: Eur Respir J 2004; 24: Suppl. 48, 633s Year: 2004 Short physical performance battery as a predictor of adverse outcomes following hospitalisation for an acute exacerbation of COPD Source: International Congress 2016 – Management of dyspnoea and exacerbations in chronic lung diseases Year: 2016